- Basic information
- CohesinDB ID: CDBP00415723
- Locus: chr21-27448270-27449349
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Data sourse: GSE138405, GSE101921, ENCSR230ZWH, ENCSR917QNE
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Cell type: Liver, Hela-Kyoto, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 87%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, NKX2-2, POU4F2, GTF2B, HOXB13, PAX6, RELA, JUNB, ETS1, SMARCA4, RAD21, KLF12, RXRA, STAT3, TAL1, MAFB, MAX, NKX3-1, FOS, NR2F2, CEBPD, OCA2, BRD2, JUN, MAFK, SP1, CTCF, AR, GATA2, REST, EGR1, FLI1, BRD4, SMC1, PDX1
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000154734,
- Related loop:
chr21:26850000-26875000~~chr21:27425000-27450000,
chr21:26850000-26875000~~chr21:27450000-27475000,
chr21:26950000-26975000~~chr21:27450000-27475000,
chr21:27100000-27125000~~chr21:27450000-27475000,
chr21:27200000-27225000~~chr21:27450000-27475000,
chr21:27225000-27250000~~chr21:27450000-27475000,
chr21:27250000-27275000~~chr21:27425000-27450000,
chr21:27300000-27325000~~chr21:27425000-27450000,
chr21:27300000-27325000~~chr21:27450000-27475000,
chr21:27450000-27475000~~chr21:27550000-27575000,
chr21:27450000-27475000~~chr21:27675000-27700000,
chr21:27450000-27475000~~chr21:28325000-28350000,
chr21:27450000-27475000~~chr21:28725000-28750000,