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Basic information

CohesinDB ID: CDBP00415732

Locus: chr21-27479348-27479900

Data sourse: GSE206145, GSE67783, GSE86191

Cell type: RPE, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 73%, "9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MYCN, ZNF263, BRF2, ZFX, POU4F2, XBP1, NME2, ZBTB48, WT1, RELA, NOTCH1, RUNX2, GRHL3, HIF1A, ARNTL, EZH2, GRHL2, CTCF, ELF3, AR, NOTCH3, BRD4, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415732