Browse_each

Basic information

CohesinDB ID: CDBP00415756

Locus: chr21-27579731-27583586

Data sourse: GSE206145, GSE206145-NatGen2015, GSE62063, GSE138105, GSE165895

Cell type: RPE, Fibroblast, SLK, HFFc6, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 71%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, NME2, SMAD3, FOXA1, ZNF823, CDK9, HOXB13, HOXC5, NOTCH1, RUNX2, NFIC, PBX4, HIF1A, GATA3, TAL1, PBX3, STAT3, FOXM1, MED1, ARNTL, NR3C1, MYOG, CEBPB, TEAD1, MYB, KLF6, TP53, JUN, TCF12, MAFK, EP300, IRF1, IRF4, SIX2, BRD4, JUND, TEAD4, FOSL2

Target gene symbol (double-evidenced CRMs): ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 53

Related genes and loops

Related gene: ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415756