- Basic information
- CohesinDB ID: CDBP00415768
- Locus: chr21-27660459-27660955
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Data sourse: GSE85526, GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 89%,
"9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, PGR, POU5F1, TOP2A, CRY1, ZFX, KDM4C, XBP1, TEAD4, ZBTB48, WT1, FOXA1, ERG, RELA, RUNX2, ARNT, HIF1A, GRHL3, ETV6, ZNF143, TEAD1, EZH2, OCA2, CTCF, AR, GATA6, NOTCH3, SCRT1, BRD4, CLOCK, ZNF528, SMC3, NCOR2, STAG1
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops