- Basic information
- CohesinDB ID: CDBP00415783
- Locus: chr21-27758206-27760949
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE116868, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, GSE165895, GSE67783, GSE86191, GSE138405, GSE36578, GSE76893, GSE101921, GSE135093, GSE206145-NatGen2015, GSE112028, GSE138105, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, GSE118494, ENCSR000EEG, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000EHX, ENCSR635OSG, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE131956, ENCSR000HPG, GSE111913, GSE38411, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, Ishikawa, HeLa-S3, GM2255, IMR-90, BCBL-1, GM18486, DKO, HFFc6, H1-hESC, SNYDER, MB157, GM12891, GM2588, GBM39, SK-N-SH, RT-112, CNCCs-H9ESC, HeLa-Tet-On, THP-1, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, Hep-G2, MCF-10A, HUVEC, HCAEC, HeLa, BGO3, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 39% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.500
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 82%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: HOXB13, GATA3
- Target gene symbol (double-evidenced CRMs): LTN1,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 19
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000198862,
- Related loop:
chr21:26848955-26851551~~chr21:27758404-27760678,
chr21:26849043-26851569~~chr21:27758641-27759952,
chr21:26849049-26852110~~chr21:27758357-27760293,
chr21:27750000-27775000~~chr21:28025000-28050000,
chr21:27750000-27775000~~chr21:28050000-28075000,
chr21:27750000-27775000~~chr21:28175000-28200000,
chr21:27750000-27775000~~chr21:28225000-28250000,
chr21:27750000-27775000~~chr21:28325000-28350000,
chr21:27750000-27775000~~chr21:28425000-28450000,
chr21:27750000-27775000~~chr21:28500000-28525000,
chr21:27750000-27775000~~chr21:28525000-28550000,
chr21:27750000-27775000~~chr21:28575000-28600000,
chr21:27750000-27775000~~chr21:28725000-28750000,
chr21:27750000-27775000~~chr21:28925000-28950000,
chr21:27758254-27761457~~chr21:28051084-28053207,
chr21:27758254-27761457~~chr21:28334487-28338171,
chr21:27758254-27761457~~chr21:28744475-28746618,
chr21:27758272-27760733~~chr21:28335606-28338251,
chr21:27758303-27760306~~chr21:28744310-28746641,
chr21:27758344-27760729~~chr21:28050094-28052904,
chr21:27758346-27760171~~chr21:28335560-28338076,
chr21:27758346-27760171~~chr21:28744222-28746677,
chr21:27758357-27760293~~chr21:28333968-28338137,
chr21:27758357-27760293~~chr21:28744250-28746679,
chr21:27758367-27760680~~chr21:28051112-28052927,
chr21:27758367-27760680~~chr21:28335663-28338245,
chr21:27758380-27760590~~chr21:28051185-28052820,
chr21:27758404-27760678~~chr21:28335576-28338198,
chr21:27758494-27760671~~chr21:28050923-28052951,
chr21:27758494-27760671~~chr21:28335562-28338194,
chr21:27758638-27760649~~chr21:28335622-28338264,
chr21:27758727-27759929~~chr21:28744528-28746609,
chr21:27759289-27760526~~chr21:28051044-28052709,