- Basic information
- CohesinDB ID: CDBP00415793
- Locus: chr21-27802628-27804018
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Data sourse: ENCSR000BLD, ENCSR230ZWH, ENCSR000FAD, GSE72082, GSE126634, GSE116868, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE138405, GSE101921, GSE135093, GSE152721, GSE206145-NatGen2015, GSE138105, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR000EEG, GSE98367, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, GSE206145, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, GSE55407, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR000HPG, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, GM19240, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, H1-hESC, SNYDER, GM18505, MB157, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, GM19238, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 37% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.433
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 73%,
"5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, AR, ZNF426, ZNF697, ZBTB11, STAT3, ZC3H11A, ZNF34
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154734,
- Related loop:
chr21:26848688-26851432~~chr21:27802305-27803923,
chr21:26848717-26851115~~chr21:27802133-27803841,
chr21:26848717-26851211~~chr21:27802381-27803695,
chr21:26848765-26851527~~chr21:27802176-27803976,
chr21:26848770-26851390~~chr21:27802290-27803924,
chr21:26848947-26851347~~chr21:27802087-27803810,
chr21:26848956-26852143~~chr21:27802108-27803785,
chr21:26880663-26882691~~chr21:27802305-27803923,
chr21:26881095-26882278~~chr21:27802335-27803696,
chr21:27775000-27800000~~chr21:28325000-28350000,
chr21:27775000-27800000~~chr21:28725000-28750000,
chr21:27800000-27825000~~chr21:27950000-27975000,
chr21:27800000-27825000~~chr21:28725000-28750000,
chr21:27802121-27804049~~chr21:28335748-28338250,