- Basic information
- CohesinDB ID: CDBP00415850
- Locus: chr21-28055025-28055673
-
Data sourse: GSE206145, GSE116344, GSE120943, GSE98367
-
Cell type: RPE, RH4, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 98%,
"5_TxWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: POU5F1, TOP2A, PRDM1, PAX5, SMARCC1
- Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS1,LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000225298,
ENSG00000198862,
- Related loop:
chr21:25600000-25625000~~chr21:28050000-28075000,
chr21:25625000-25650000~~chr21:28050000-28075000,
chr21:26825000-26850000~~chr21:28050000-28075000,
chr21:26850000-26875000~~chr21:28050000-28075000,
chr21:27200000-27225000~~chr21:28050000-28075000,
chr21:27550000-27575000~~chr21:28050000-28075000,
chr21:27564022-27565753~~chr21:28050923-28052951,
chr21:27699913-27702170~~chr21:28051110-28052908,
chr21:27699952-27702148~~chr21:28050939-28053207,
chr21:27699963-27702208~~chr21:28050939-28052956,
chr21:27700000-27725000~~chr21:28050000-28075000,
chr21:27700282-27702347~~chr21:28051033-28052927,
chr21:27700287-27702114~~chr21:28050094-28052904,
chr21:27700325-27702096~~chr21:28051197-28052726,
chr21:27700355-27702199~~chr21:28051112-28052927,
chr21:27750000-27775000~~chr21:28050000-28075000,
chr21:27758254-27761457~~chr21:28051084-28053207,
chr21:27758344-27760729~~chr21:28050094-28052904,
chr21:27758367-27760680~~chr21:28051112-28052927,
chr21:27758380-27760590~~chr21:28051185-28052820,
chr21:27758494-27760671~~chr21:28050923-28052951,
chr21:27759289-27760526~~chr21:28051044-28052709,
chr21:28050000-28075000~~chr21:28225000-28250000,
chr21:28050000-28075000~~chr21:28300000-28325000,
chr21:28050000-28075000~~chr21:28325000-28350000,
chr21:28050000-28075000~~chr21:28500000-28525000,
chr21:28050000-28075000~~chr21:28525000-28550000,
chr21:28050000-28075000~~chr21:28725000-28750000,
chr21:28050000-28075000~~chr21:28925000-28950000,
chr21:28050094-28052904~~chr21:28744171-28746673,
chr21:28050923-28052951~~chr21:28744431-28746621,
chr21:28050939-28053207~~chr21:28335622-28338264,
chr21:28050939-28053207~~chr21:28744399-28746641,
chr21:28050942-28052908~~chr21:28744204-28746655,
chr21:28050985-28053261~~chr21:28744200-28746589,
chr21:28050991-28052838~~chr21:28521403-28523335,
chr21:28050991-28052838~~chr21:28744455-28746667,
chr21:28051032-28053224~~chr21:28335606-28338251,
chr21:28051084-28053207~~chr21:28334487-28338171,
chr21:28051112-28052922~~chr21:28744497-28746545,
chr21:28051112-28052927~~chr21:28335663-28338245,
chr21:28051112-28052927~~chr21:28521324-28523315,
chr21:28051112-28052927~~chr21:28741981-28743659,
chr21:28051112-28052927~~chr21:28744452-28746493,
chr21:28051170-28052632~~chr21:28744510-28746501,
chr21:28051197-28052726~~chr21:28744207-28746569,
chr21:28051210-28052762~~chr21:28744462-28746595,