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Basic information

CohesinDB ID: CDBP00415855

Locus: chr21-28064474-28066923

Data sourse: GSE206145, GSE111537, GSE62063, GSE206145-NatGen2015

Cell type: RPE, Fibroblast, OCI-AML-3, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,Mau2,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 73%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, NR3C1, PGR, MYC, ETV1, POU2F3, EZH2, MLL, FOXA1, T, FOS, SPI1, ERG

Target gene symbol (double-evidenced CRMs): ADAMTS1,LTN1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298, ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00415855