- Basic information
- CohesinDB ID: CDBP00415899
- Locus: chr21-28214838-28216276
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Data sourse: ENCSR000EFJ, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE68388, GSE138105, GSE116344, GSE108869, ENCSR000ECS, GSE165895
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Cell type: RPE, Fibroblast, RH4, SLK, HeLa-S3, IMR-90, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 75%,
"7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, FOXA1, HLF, ATF3, PRDM1, TP63, JMJD1C, MAF, TEAD1, ETV1, NFE2L2, ESR1, MLL, USF2, JUN, CTCF, BAF155, EP300, RFX5, DEK, PDX1, TFAP2C, POU5F1, TOP2A, CTBP1, STAT1, TBP, ERG, HOXC5, MYC, RAD21, STAT3, NKX3-1, RCOR1, VDR, NR3C1, CEBPB, ZNF750, GRHL2, SPI1, EHF, GATA2, FLI1, CEBPA, NKX2-2, EZH2phosphoT487, SIN3A, SMAD3, SMARCC1, RUNX2, GATA4, GR, PBX4, ARNT, NRF1, DAXX, ATF2, FOS, MED1, CEBPD, MYB, PIAS1, BCL11A, REST, ZHX1, ATF7, SMC3, PPARG, FOXA2, CHD2, MAFF, HOXB13, KDM1A, RELA, JUNB, GATA3, MAX, KLF4, CEBPG, TCF7L2, NFKB1, ELF3, BHLHE40, AR, BRD4, JUND, AHR
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops