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Basic information

CohesinDB ID: CDBP00415902

Locus: chr21-28227105-28227445

Data sourse: GSE206145-NatGen2015, GSE72082

Cell type: Fibroblast, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 85%, "5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CHD8, FOXA2, POU5F1, TBL1X, ZFX, XBP1, ZBTB48, WT1, FOXA1, HOXB13, ERG, RELA, MYC, RUNX2, BRG1, GRHL3, HIF1A, GABPA, NKX3-1, ZNF143, SFPQ, TLE3, PIAS1, EZH2, LMO2, ESR1, MED26, CTCF, BAF155, GSPT2, AR, GATA2, ARID1A, EGLN2, ASH2L, NOTCH3, BRD4, FOXP1

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298,

eachgene

Deatailed information for cohesin site CDBP00415902