- Basic information
- CohesinDB ID: CDBP00415904
- Locus: chr21-28234195-28235962
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE73207, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE67783, GSE86191, GSE76893, GSE101921, GSE135093, GSE206145-NatGen2015, GSE120943, ENCSR703TNG, GSE106870, GSE116344, GSE98367, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, ENCSR167MTG, ENCSR000HPG, GSE111913, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE83726, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, CVB-hiPSC, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, Ishikawa, HeLa-S3, IMR-90, DKO, H1-hESC, Monocytes, TF-1, GM2588, SK-N-SH, RT-112, THP-1, Macrophage, HUES64, MCF-7, HCT-116, HL-60, Hep-G2, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 20% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.667
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM28, ZFX
- Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000154734,
ENSG00000225298,
- Related loop:
chr21:26800000-26825000~~chr21:28225000-28250000,
chr21:26825000-26850000~~chr21:28225000-28250000,
chr21:26875000-26900000~~chr21:28225000-28250000,
chr21:27300000-27325000~~chr21:28225000-28250000,
chr21:27550000-27575000~~chr21:28225000-28250000,
chr21:27750000-27775000~~chr21:28225000-28250000,
chr21:27825000-27850000~~chr21:28225000-28250000,
chr21:28050000-28075000~~chr21:28225000-28250000,
chr21:28075000-28100000~~chr21:28225000-28250000,
chr21:28100000-28125000~~chr21:28225000-28250000,
chr21:28125000-28150000~~chr21:28225000-28250000,
chr21:28225000-28250000~~chr21:28325000-28350000,
chr21:28225000-28250000~~chr21:28375000-28400000,
chr21:28225000-28250000~~chr21:28425000-28450000,
chr21:28225000-28250000~~chr21:28450000-28475000,
chr21:28225000-28250000~~chr21:28525000-28550000,
chr21:28225000-28250000~~chr21:28625000-28650000,
chr21:28225000-28250000~~chr21:28650000-28675000,
chr21:28225000-28250000~~chr21:28725000-28750000,
chr21:28225000-28250000~~chr21:28800000-28825000,