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Basic information

CohesinDB ID: CDBP00415907

Locus: chr21-28240623-28241036

Data sourse: ENCSR000EFJ, ENCSR230ZWH, GSE206145, GSE206145-NatGen2015, ENCSR917QNE

Cell type: RPE, Liver, Fibroblast, IMR-90

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,NIPBL,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 83%, "5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, POU4F2, XBP1, FOXA1, RELA, JUNB, RUNX2, GR, RAD21, GRHL3, RXRA, GABPA, STAT3, TAL1, GATA1, MED1, NR3C1, NR2F2, TRIM28, SMAD1, EZH2, USF2, JUN, BCL11A, SP1, AR, GATA2, BRD4

Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298,

eachgene

Deatailed information for cohesin site CDBP00415907