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Basic information

CohesinDB ID: CDBP00415971

Locus: chr21-28518339-28518971

Data sourse: GSE206145, GSE101921, ENCSR000HPG, GSE94872

Cell type: RPE, HUVEC, HCAEC, IMR-90

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SMC3,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 64%, "5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, SOX2, XBP1, FOXA1, RXRB, KDM3A, TFAP4, ATF3, NFIC, CTCFL, CHD7, PRDM1, MXD4, PAX5, CDX2, MYOG, TEAD1, TRIM28, BCLAF1, KLF6, SNAI2, ELF1, RCOR2, ESR1, OCA2, HNF1B, PITX3, CTCF, TCF12, JUN, BAF155, KLF1, EP300, SOX5, GATA6, IRF4, RFX5, E2F4, E2F1, SMC1, FOXA3, GTF2F1, PDX1, RBPJ, TFAP2C, GATAD2A, POU2F2, CHD8, NANOG, ZSCAN5D, ZNF263, MYCN, POU5F1, TOP2A, ZNF317, ZBTB48, STAT1, SRF, GATAD1, SAP130, ARID3A, SP4, HNF4G, ERG, ASCL1, ETS1, EZH1, MYC, SMARCA4, ZNF2, RAD21, FOXP2, GRHL3, RXRA, GABPA, STAT3, XRCC5, ZNF614, NKX3-1, APC, RCOR1, NFE2, NR2F6, MIER3, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, EZH2, JMJD6, ZNF652, EBF3, GABPB1, ZHX2, SPI1, MIXL1, IRF1, GATA2, ZNF644, MXD3, FLI1, ZGPAT, SMARCA5, MRTFB, NFIL3, MYF5, ETV5, RUNX1, THAP11, SMC1A, BCL6, CBX1, NKX2-2, CEBPA, CRY1, SOX13, ZFX, POU4F2, SIN3A, SMAD3, ZNF654, SP5, TRIM22, TWIST1, PRDM10, RARA, ZNF384, ZBTB2, ZNF35, CREBBP, RUNX2, CDK6, GATA4, GR, NRF1, ARNT, ZNF48, HMGB2, ZEB2, SMAD4, MAFB, ZNF10, FOS, HMGXB4, MED1, TEAD3, ZEB1, MYB, SMAD1, ZBTB18, SETDB1, BCL11A, GSPT2, HNF4A, IKZF5, REST, ZHX1, ASH2L, TCF3, FOXP1, BCOR, SMC3, NCOR2, STAG1, STAG2, MEF2B, PPARG, FOXA2, TBL1X, EBF1, CHD2, MIER2, ZSCAN16, GTF2B, WT1, MEF2C, CDK9, ZNF580, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, ISL1, SP140, ZIC2, HIF1A, TCF4, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, HAND2, TLE3, KLF4, CEBPG, BCL11B, NR2F1, TCF7L2, KDM5B, NEUROG2, TP53, MED, ZSCAN22, MYOD1, PHOX2B, BRD2, ELF3, KAT8, ARRB1, TBX21, NFKBIZ, AR, PAX3-FOXO1, ARID4B, TAF1, EGLN2, ZBTB42, ZBTB26, NCOR1, NOTCH3, BRD4, JUND, CUX1, MAZ, TBX2, ZFP42, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): LINC00113,LTN1,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298, ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00415971