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Basic information

CohesinDB ID: CDBP00415974

Locus: chr21-28523395-28523853

Data sourse: GSE101921, GSE206145-NatGen2015, ENCSR230ZWH

Cell type: Liver, Fibroblast, HCAEC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 90%, "7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, SMARCA2, SOX2, FOXA1, LYL1, CHD7, JMJD1C, TRIM28, KLF6, ETV1, LMO2, ESR1, HNF1B, JUN, CTCF, TCF12, BAF155, IRF4, SMC1, KMT2B, TFAP2C, POU2F2, MYCN, ERF, STAT1, ERG, HOXC5, ETS1, MYC, SMARCA4, RAD21, GRHL3, GABPA, NKX3-1, GFI1, ARNTL, CEBPB, KMT2A, CREB1, EBF3, SPI1, EHF, IRF1, GATA2, SIX2, FLI1, RUNX1, SMC1A, CEBPA, TWIST1, SMARCC1, ZBTB2, ZNF384, RUNX2, DAXX, PBX4, ARNT, HMGB2, PBX3, FOS, CDK8, MED1, CEBPD, MYB, PIAS1, SETDB1, EVI1, SP1, HNF4A, HOXA9, FOXP1, SMC3, STAG1, STAG2, PPARG, FOXA2, MEIS1, GTF2B, FOXF1, HOXB13, KDM1A, YY1, RELA, JUNB, BRG1, ISL1, HIF1A, TAL1, MAX, ZNF143, HAND2, KLF4, NR2F2, KDM5B, MED, PHOX2B, ELF3, AR, ZBTB16, HSF1, BRD4, TBX2

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113,LTN1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298, ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00415974