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Basic information

CohesinDB ID: CDBP00415978

Locus: chr21-28549840-28550779

Data sourse: GSE206145-NatGen2015, GSE72082, GSE165895

Cell type: MCF-7, Fibroblast, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 83%, "7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, PGR, NANOG, MEF2B, FOXA2, NKX2-2, TOP2A, SMAD3, DUX4, FOXA1, HOXB13, SMARCC1, HNF4G, HOXC5, ERG, RELA, MYC, RUNX2, GATA4, NFIC, GR, BRG1, SMARCA4, PBX4, DAXX, TOP1, GATA3, GABPA, STAT3, PBX3, TAL1, MAFB, FOS, NKX3-1, MED1, VDR, TLE3, CDX2, CEBPB, NR3C1, CSNK2A1, TEAD1, CREB1, PIAS1, ETV1, EZH2, ESR1, KLF8, ZNF334, ZNF652, CTCF, TCF12, JUN, BAF155, KLF1, EP300, SPI1, AR, REST, GATA2, ARID1A, SIX2, BRD4, JUND, CTBP2, FOXP1, PDX1, AHR

Target gene symbol (double-evidenced CRMs): ADAMTS1,LTN1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298, ENSG00000198862,

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Deatailed information for cohesin site CDBP00415978