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Basic information

CohesinDB ID: CDBP00415979

Locus: chr21-28554707-28555498

Data sourse: GSE72082, GSE86191, GSE67783, ENCSR000BLS, ShirahigeLab, ShirahigeLab-NatGen2015, GSE68388

Cell type: RPE, Fibroblast, HCT-116, Hep-G2, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 68%, "7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: BCL6, FOXA2, SOX13, ZFX, MIER2, WT1, ZSCAN5A, FOXA1, TCF7, SAP130, ETV5, ZNF580, HNF4G, TFAP4, YY1, RELA, RUNX2, RAD21, ZIC2, CBFB, SMAD4, ZNF614, HNRNPH1, NR2F6, TEAD3, CREB1, NR2F1, SETDB1, GABPB1, JUN, ELF3, CTCF, ZHX2, SPI1, MIXL1, HNF4A, ASH2L, MAZ, GATAD2A, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415979