- Basic information
- CohesinDB ID: CDBP00415996
- Locus: chr21-28626740-28628205
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 75%,
"5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, TLE3, NANOG, GATA2, ARID1A, FOXA2, POU5F1, PIAS1, PRDM1, ARNT, FOXA1, E2F1, TAL1, CTCF, NKX3-1, HOXB13, ERG
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000154734,
- Related loop:
chr21:25350000-25375000~~chr21:28625000-28650000,
chr21:26825000-26850000~~chr21:28625000-28650000,
chr21:28225000-28250000~~chr21:28625000-28650000,
chr21:28325000-28350000~~chr21:28625000-28650000,
chr21:28375000-28400000~~chr21:28625000-28650000,
chr21:28425000-28450000~~chr21:28625000-28650000,
chr21:28500000-28525000~~chr21:28625000-28650000,
chr21:28525000-28550000~~chr21:28625000-28650000,
chr21:28625000-28650000~~chr21:28725000-28750000,