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Basic information

CohesinDB ID: CDBP00415999

Locus: chr21-28641665-28643259

Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR167MTG, GSE206145-GSE177045, GSE67783, GSE72082, GSE111913, ENCSR000BLY, ENCSR000BLS, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, ENCSR000EHX, GSE83726, ENCSR703TNG, GSE25021, GSE97394

Cell type: MCF-7, H1-hESC, Fibroblast, RH4, Hep-G2, HUES64, SK-N-SH, RT-112, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.889

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 82%, "5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CBX1, CHD2, SIN3A, CTBP1, FOXA1, KDM1A, CREBBP, AHR, RUNX2, MYC, GR, RAD21, ARNT, HIF1A, GATA3, SMARCE1, NRIP1, GATA1, ZNF143, RCOR1, HAND2, TLE3, NR3C1, ESRRA, TEAD1, PIAS1, TCF7L2, KDM5B, ZNF217, TP53, ESR1, GRHL2, ZNF334, EBF3, TRPS1, JUN, ZHX2, TCF12, EP300, TFAP2A, AR, DPF2, HDAC2, GATA2, EGLN2, BRD4, CTBP2, JUND, MBD2, ZIM3, ZNF24, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415999