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Basic information

CohesinDB ID: CDBP00416000

Locus: chr21-28644180-28645338

Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR000EFJ, GSE72082, ENCSR000BLY, GSE105028, GSE101921, ENCSR000ECE, GSE85526, GSE206145-NatGen2015, ENCSR000EHX, GSE68388, GSE206145, ENCSR703TNG, GSE25021, GSE97394, GSE165895

Cell type: MCF-7, H1-hESC, HMEC, Fibroblast, MCF-10A, RPE, HEKn, HUES64, H9-hESC, IMR-90, SK-N-SH, HuCC-T1, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 10% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.856

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 79%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMC1A, RELA, CREBBP, JUNB, RUNX2, CDK6, GR, RAD21, GATA3, STAT3, TAL1, FOS, GATA1, MED1, ZNF750, CEBPB, NR3C1, STAG1, ESR1, NFKB1, SETDB1, CTCF, JUN, BCL11A, AR, BRD4, SMC1, STAG2

Target gene symbol (double-evidenced CRMs): ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00416000