- Basic information
- CohesinDB ID: CDBP00416100
- Locus: chr21-29048000-29048139
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 66%,
"5_TxWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, CEBPB, HOXB13, ETS1, RUNX2, ZNF264, CDK6, SMAD5, ZSCAN16, PKNOX1, BRD4, DUX4, FOXP1, PRDM9, FOXA1, ZSCAN4, CTCF, RBM22, SUPT5H, SPI1
- Target gene symbol (double-evidenced CRMs): USP16
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000156256,
- Related loop:
chr21:25750000-25775000~~chr21:29050000-29075000,
chr21:28950000-28975000~~chr21:29050000-29075000,
chr21:29025000-29050000~~chr21:31675000-31700000,
chr21:29025000-29050000~~chr21:32325000-32350000,
chr21:29025000-29050000~~chr21:32750000-32775000,
chr21:29025000-29050000~~chr21:33525000-33550000,
chr21:29050000-29075000~~chr21:29300000-29325000,
chr21:29050000-29075000~~chr21:31675000-31700000,
chr21:29050000-29075000~~chr21:32300000-32325000,
chr21:29050000-29075000~~chr21:32325000-32350000,
chr21:29050000-29075000~~chr21:32350000-32375000,
chr21:29050000-29075000~~chr21:32625000-32650000,
chr21:29050000-29075000~~chr21:32725000-32750000,
chr21:29050000-29075000~~chr21:32750000-32775000,
chr21:29050000-29075000~~chr21:33500000-33525000,
chr21:29050000-29075000~~chr21:33550000-33575000,
chr21:29050000-29075000~~chr21:39175000-39200000,