Deatailed information for gene ENSG00000156256
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009956
- Gene Symbol: USP16
- Ensembl ID: ENSG00000156256
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Gene locus: chr21:29024628-29054488
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-28951723-28951953,
chr21-28959314-28959751,
chr21-28961868-28962960,
chr21-28968738-28969112,
chr21-28991642-28993980,
chr21-29001800-29004153,
chr21-29018321-29020227,
chr21-29021625-29022143,
chr21-29023611-29026769,
chr21-29029109-29029871,
chr21-29033430-29033597,
chr21-29035392-29035855,
chr21-29048000-29048139,
chr21-29051564-29051818,
chr21-29053116-29053515,
chr21-29054263-29054943,
chr21-29057293-29057849,
chr21-29058619-29059007,
chr21-29296491-29303668,
chr21-29304154-29305335,
chr21-29305747-29309169,
chr21-29313792-29314472,
chr21-29315462-29315610,
chr21-29315990-29317552,
chr21-29318199-29318712,
chr21-29319627-29319847,
chr21-29320109-29320295,
chr21-29320703-29320863,
chr21-29321259-29321494,
chr21-29321914-29322368,
chr21-29322647-29323646,
chr21-29323911-29324647,
chr21-29324965-29325251,
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Co-expression with cohesin genes Rho = 0.7593
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.216
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.880
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: HEK293T,ARPE-19,GM12878,CyT49-endoderm,Hep-G2,IMR-90,K-562,H1-hESC,HT-1376,HFF-hTERT,HAP1,HFFc6,Jurkat,PAEC,H9-hESC,BMEC,CyT49-hESC
- Related loop:
chr21:17775000-17800000~~chr21:29000000-29025000,
chr21:25325000-25350000~~chr21:29000000-29025000,
chr21:25725000-25750000~~chr21:29000000-29025000,
chr21:25750000-25775000~~chr21:29050000-29075000,
chr21:28950000-28975000~~chr21:29050000-29075000,
chr21:28991455-28993844~~chr21:29023842-29026326,
chr21:28991517-28993800~~chr21:29024190-29026094,
chr21:28991528-28993711~~chr21:29024204-29026148,
chr21:28991579-28993764~~chr21:29023633-29025850,
chr21:28991614-28993817~~chr21:29023881-29026318,
chr21:28991626-28993358~~chr21:29018475-29019750,
chr21:28991807-28993775~~chr21:29023855-29025783,
chr21:29002049-29004026~~chr21:29018446-29019818,
chr21:29025000-29050000~~chr21:31675000-31700000,
chr21:29025000-29050000~~chr21:32325000-32350000,
chr21:29025000-29050000~~chr21:32750000-32775000,
chr21:29025000-29050000~~chr21:33525000-33550000,
chr21:29050000-29075000~~chr21:29300000-29325000,
chr21:29050000-29075000~~chr21:31675000-31700000,
chr21:29050000-29075000~~chr21:32300000-32325000,
chr21:29050000-29075000~~chr21:32325000-32350000,
chr21:29050000-29075000~~chr21:32350000-32375000,
chr21:29050000-29075000~~chr21:32625000-32650000,
chr21:29050000-29075000~~chr21:32725000-32750000,
chr21:29050000-29075000~~chr21:32750000-32775000,
chr21:29050000-29075000~~chr21:33500000-33525000,
chr21:29050000-29075000~~chr21:33550000-33575000,
chr21:29050000-29075000~~chr21:39175000-39200000,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFI8649RQJ, ENCSR194SRI, 4DNFIMROE6N4, 4DNFI5SUHCGZ, ENCSR852KQC, ENCSR361AYD, ENCSR146FPM, ENCSR410MDC, 4DNFII6AN691, 4DNFIKYXMF1E, 4DNFIYD8LO9Z, ENCSR668RDP, 4DNFICSTCJQZ, ENCSR981FNA, ENCSR587DSF, 4DNFIIMZB6Y9, 4DNFI1E6NJQJ, GSE52457, 4DNFI3A3VYWU, Direct, 4DNFI6XD6JAQ, 4DNFIYDBBSE3, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, 4DNFIK61ILGM, GSE44267, 4DNFIPAF4PYT, ENCSR110JOO, 4DNFIDKJFK2S, ENCSR933UZH, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, GSE105028, ENCSR507AHE, 4DNFII84FBKM
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: SLK,Kelly
- Cohesin-DEGs, number of studies: 3
- Cohesin-DEGs, study: GSE115253,GSE138937
- Cohesin-DEGs, subunit: CTCF,Rad21,BORIS