- Basic information
- CohesinDB ID: CDBP00416089
- Locus: chr21-29001800-29004153
-
Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, GSE126634, ENCSR000EGW, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, GSE25021, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE165895, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE138405, GSE86191, GSE76893, GSE101921, GSE206145-NatGen2015, GSE120943, ENCSR198ZYJ, GSE138105, GSE130135, ENCSR703TNG, GSE116344, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE206145, GSE62063, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, ENCSR767DFK, ENCSR495WGO, GSE97394, ENCSR167MTG, GSE110061, GSE129526, ENCSR000HPG, GSE111913, GSE155324, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE126990, GSE50893, GSE126755, ENCSR000ECS, GSE38411
-
Cell type: MDM, RH4, GM10847, GM2610, SLK, OCI-AML-3, HSPC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, RT-112, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, Ramos, HEK293T, Hep-G2, Neurons-H1, A-549, HCAEC, GM19238, Neutrophil, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 31% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.422
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 27%,
"1_TssA": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NEUROD1, TOP2A, BRD4, BRD2, SUPT5H
- Target gene symbol (double-evidenced CRMs): RWDD2B,USP16
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 14
- Related genes and loops