Deatailed information for gene ENSG00000156253
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009955
- Gene Symbol: RWDD2B
- Ensembl ID: ENSG00000156253
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Gene locus: chr21:29004383-29019349
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-28991642-28993980,
chr21-28999955-29001312,
chr21-29001800-29004153,
chr21-29010641-29012359,
chr21-29013377-29014029,
chr21-29015368-29015829,
chr21-29017088-29017991,
chr21-29018321-29020227,
chr21-29021625-29022143,
chr21-29023611-29026769,
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Co-expression with cohesin genes Rho = 0.4926
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
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Gene expression across tissues (TPM):
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Tissue specificity of gene (Gini-coefficient): 0.239
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
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Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.749
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
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Involved cell types for loop evidence: ARPE-19,GM12878,Hep-G2,K-562,H1-hESC,HT-1376,Jurkat,HFFc6,PAEC,H9-hESC
- Related loop:
chr21:17775000-17800000~~chr21:29000000-29025000,
chr21:25325000-25350000~~chr21:29000000-29025000,
chr21:25350000-25375000~~chr21:28975000-29000000,
chr21:25725000-25750000~~chr21:28975000-29000000,
chr21:25725000-25750000~~chr21:29000000-29025000,
chr21:28991455-28993844~~chr21:29023842-29026326,
chr21:28991517-28993800~~chr21:29024190-29026094,
chr21:28991528-28993711~~chr21:29024204-29026148,
chr21:28991579-28993764~~chr21:29023633-29025850,
chr21:28991614-28993817~~chr21:29023881-29026318,
chr21:28991626-28993358~~chr21:29018475-29019750,
chr21:28991807-28993775~~chr21:29023855-29025783,
chr21:29002049-29004026~~chr21:29018446-29019818,
- Cohesin-loop type: HiC,Direct,ChIAPET
- Cohesin-loop study:
ENCSR110JOO, Direct, 4DNFITUOMFUQ, ENCSR668RDP, ENCSR933UZH, 4DNFIDZT7PR8, 4DNFI1UEG1HD, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFII84FBKM, ENCSR361AYD, ENCSR146FPM, ENCSR981FNA, ENCSR587DSF, ENCSR410MDC
- Cohesin-loop subunit: Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
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Involved cell types for DEG evidence: U2OS,CMK,HPC,P3HR-1
- Cohesin-DEGs, number of studies: 5
- Cohesin-DEGs, study: GSE140651,GSE119828,GSE154086,GSE89799
- Cohesin-DEGs, subunit: CdLS,SMC1,Rad21,SA2