Deatailed information for cohesin site CDBP00416095

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  • Basic information
  • CohesinDB ID: CDBP00416095
  • Locus: chr21-29021625-29022143
  • Data sourse: GSE67783, ENCSR153HNT
  • Cell type: K-562, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 0% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.978
  • Subunit: SA1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 66%, "15_Quies": 20%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, FOXA1, HLF, RXRB, MLL4, KDM3A, HDGF, MEN1, THAP1, IKZF3, ZNF429, MORC2, PAX5, SFPQ, TEAD1, SNAPC1, LMO2, OCA2, MED26, PITX3, HDAC8, ZNF561, ZNF577, ARID5B, E4F1, ZNF75A, SOX5, E2F4, DEK, ZNF528, RFX3, KMT2B, GATAD2A, NANOG, POU5F1, BRD3, TOP2A, ZNF263, CTBP1, ERF, STAT1, SAP130, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, RFX1, FOXK2, UBN1, RCOR1, NR2F6, CD74, NFRKB, CEBPB, HNRNPL, CREB1, DDX21, BMPR1A, GABPB1, ELF4, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, HCFC1, NR2C2, MXI1, ZNF785, RELB, EP400, RUNX1, CEBPA, NKX2-2, HDAC1, IRF3, TET2, TBX3, SP5, TRIM22, SMARCC1, PRDM10, ZNF549, ZXDC, ZBTB2, ELK1, ZBTB10, ATF2, FOXM1, SP2, SMARCB1, GMEB1, PML, PIAS1, SMAD1, C11orf30, EVI1, MBD1, STAT5A, GSPT2, IKZF5, ARID2, OVOL3, RBM25, ZSCAN31, AFF1, MBD2, ELL2, ZNF704, ETV4, NFATC3, MEF2B, ZNF207, CBX3, CREM, CHD2, NFATC1, PAF1, ZSCAN16, WT1, MEF2C, CREB3L1, NEUROD1, JUNB, ZFP36, BATF, SPIB, PLAG1, KLF4, ZFP69B, BCL11B, ZBTB6, MED, BCL6B, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, ZBTB26, NCOR1, ILF3, SMARCA2, ZNF660, XBP1, KDM4B, ZNF101, PBX2, ATF3, ZFP64, RUNX3, CBFB, TP63, MITF, ZNF467, MAF, JMJD1C, INTS11, ELF1, RBM39, SNAI2, KLF10, SMAD5, JUN, TAF3, CTCF, LMO1, ZBTB20, MNT, DPF2, SIX5, IRF4, DDX20, ZNF423, ZNF350, ZNF280A, PDX1, RBPJ, MLX, TFAP2C, MTA2, ZBTB17, ZBTB48, ZSCAN21, ZNF317, NONO, SRF, DDX5, NBN, PBX1, KDM4A, HOMEZ, FOXP2, ZNF2, RXRA, NKX3-1, PRDM14, MIER3, LEF1, HNRNPH1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, KDM5A, ZNF146, SMARCA5, NFIL3, CC2D1A, THAP11, LDB1, SOX13, AFF4, POU4F2, ZNF770, ZNF513, ZMIZ1, ZNF18, CEBPZ, SP3, DAXX, ARNT, BACH1, ZNF48, ZEB2, NFYA, PBX3, MAFB, ZNF10, HMGXB4, TEAD3, DIDO1, ZXDB, U2AF1, TAF7, KLF9, ZBTB18, TBX5, USF1, SP1, BCL11A, NKX2-5, ZNF479, ATF7, ASH2L, GLIS2, SMC3, MLLT1, STAG1, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MEIS1, MAFF, ESR2, ZNF580, ZKSCAN1, BCL3, KDM1A, KLF7, ZNF441, ZIC2, PCGF1, GATA3, KLF15, TAL1, NRIP1, ZNF143, AGO2, MTA1, ZNF141, TP53, ZSCAN22, NFKB1, BRD2, PHF5A, KAT8, ARRB1, TBX21, EGR1, RB1, RNF2, IKZF2, BRD4, JUND, SPIN1, ZSCAN23, TBX2, PGR, FANCL, SOX2, PATZ1, LEO1, UBTF, TFAP4, SIN3B, ATF4, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, SAP30, ESR1, ZNF217, ZNF524, KLF1, SOX9, SOX4, E2F6, TRIM24, RFX5, PRKDC, U2AF2, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ASH1L, ZSCAN5A, ELK4, ERG2, SP4, TBP, HNF4G, HOXC5, SMARCC2, ETS1, MYC, ZNF671, ARID1B, ZNF24, KLF12, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, INO80, DNMT3B, SRSF3, EZH2, ZNF652, PHF8, SPI1, PCBP1, HDAC2, INTS13, RBP2, ZNF76, NFYB, ETV5, BCL6, SIN3A, ZBTB12, ERG3, MEF2A, RARA, ZNF384, NFYC, CREBBP, ZNF35, ZNF518A, SMAD4, CDK8, CSNK2A1, ZEB1, SPDEF, SUPT16H, NCOA1, GTF3C2, SREBF2, RBM22, MAFK, NR4A1, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, NCOR2, ZNF34, CXXC4, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, ZNF30, JDP2, ZNF574, FOXO3, RELA, TARDBP, SKIL, MAX, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, RUVBL1, MYOD1, T, KMT2D, AR, YAP1, ZNF324, DMAP1, AHR, FOSL2, ZNF391, HMG20A, E2F7, MEIS2, SUZ12, RBFOX2, ZFHX2, LYL1, INSM2, NFIC, PRDM1, MECOM, CDX2, ZNF629, KLF5, BCLAF1, TRIM28, ETV1, RCOR2, COBLL1, USF2, TCF12, BAF155, EP300, GATA6, PRDM4, GLI4, SOX6, RAD51, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, RUNX1T1, ID3, CDK7, GATAD1, GMEB2, ARID3A, MIER1, ZNF341, RAD21, PROX1, APC, ZNF614, XRCC5, NFE2, TCF25, ZNF639, ARNTL, FEZF1, TFE3, HBP1, EHF, IRF1, SREBF1, ZGPAT, MRTFB, MYF5, ATF1, PTBP1, ZNF45A, SMC1A, CBX1, SIRT6, ZNF335, ZFX, FIP1L1, SMAD3, TWIST1, IRF2, PRPF4, NOTCH1, RUNX2, CDK6, GATA4, OSR2, ZNF184, NRF1, PBX4, NR2C1, FOS, SUPT5H, CHD1, TGIF2, MED1, CEBPD, MYB, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, PHF20, ZBTB7A, PHIP, TCF3, SKI, NELFA, ZNF283, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, ZNF148, ASXL1, ZNF610, SP140, HIF1A, OTX2, GATA1, CEBPG, SP7, NCOA3, NR2F2, ZNF687, ZNF213, ZNF843, BHLHE40, NFKBIZ, TAF1, ZBTB40, ZBTB42, NOTCH3, CLOCK, MAZ, BRCA1
  • Target gene symbol (double-evidenced CRMs): RWDD2B,USP16
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 1
  • Related genes and loops
  • Related gene: ENSG00000156253, ENSG00000156256,
  • Related loop: chr21:17775000-17800000~~chr21:29000000-29025000, chr21:25325000-25350000~~chr21:29000000-29025000, chr21:25725000-25750000~~chr21:29000000-29025000, chr21:28991455-28993844~~chr21:29023842-29026326, chr21:28991517-28993800~~chr21:29024190-29026094, chr21:28991528-28993711~~chr21:29024204-29026148, chr21:28991579-28993764~~chr21:29023633-29025850, chr21:28991614-28993817~~chr21:29023881-29026318, chr21:28991626-28993358~~chr21:29018475-29019750, chr21:28991807-28993775~~chr21:29023855-29025783, chr21:29002049-29004026~~chr21:29018446-29019818, chr21:29025000-29050000~~chr21:31675000-31700000, chr21:29025000-29050000~~chr21:32325000-32350000, chr21:29025000-29050000~~chr21:32750000-32775000, chr21:29025000-29050000~~chr21:33525000-33550000,
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