- Basic information
- CohesinDB ID: CDBP00416126
- Locus: chr21-29114089-29115572
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Data sourse: ENCSR000BTU, GSE105004, GSE131606, GSE138405, GSE129526, GSE206145, GSE206145-NatGen2015, GSE135093, ENCSR000EDE, GSE68388, GSE126990, GSE108869, ENCSR000ECS, GSE165895
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Cell type: RPE, Fibroblast, HCT-116, Hela-Kyoto, HEK293T, Ishikawa, HeLa-S3, HeLa, IMR-90, HFFc6, HuCC-T1, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SIN3A, ZFX, XBP1, ZBTB17, MAZ, PHOX2B
- Target gene symbol (double-evidenced CRMs): MAP3K7CL,BACH1,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 56
- Number of somatic mutations (non-coding): 4
- Related genes and loops