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Basic information

CohesinDB ID: CDBG00009958

Gene Symbol: MAP3K7CL

Ensembl ID: ENSG00000156265

Gene locus: chr21:29077632-29175889 Strand: +

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-28951723-28951953, chr21-28959314-28959751, chr21-28961868-28962960, chr21-28968738-28969112, chr21-29072018-29074622, chr21-29074884-29075433, chr21-29075829-29075966, chr21-29076222-29078000, chr21-29079180-29079737, chr21-29080209-29080956, chr21-29081224-29081617, chr21-29087569-29094441, chr21-29094711-29095387, chr21-29095862-29096053, chr21-29096546-29097199, chr21-29098256-29099251, chr21-29099455-29101135, chr21-29102975-29105726, chr21-29106649-29107301, chr21-29113495-29113864, chr21-29114089-29115572, chr21-29117017-29117809, chr21-29121756-29123302, chr21-29124971-29125928, chr21-29128321-29128628, chr21-29129649-29131620, chr21-29136537-29136906, chr21-29140788-29141101, chr21-29143226-29143788, chr21-29144173-29147556, chr21-29148256-29148957, chr21-29150671-29151440, chr21-29152909-29153775, chr21-29155290-29156050, chr21-29157109-29157760, chr21-29159810-29160209, chr21-29161044-29161329, chr21-29161992-29169830, chr21-29170354-29172726, chr21-29174072-29177013, chr21-29177913-29178352, chr21-29180907-29186165, chr21-29187616-29191797, chr21-29192039-29192372, chr21-29192661-29199386, chr21-29202234-29202641, chr21-29205492-29205830, chr21-29207162-29210453, chr21-29211818-29212688, chr21-29213561-29214401, chr21-29215632-29220031, chr21-29220845-29223441, chr21-29223760-29224997, chr21-29277558-29277792, chr21-29281119-29281788, chr21-29287057-29289061, chr21-29289505-29290651, chr21-29293004-29294050, chr21-29295121-29295701, chr21-29296491-29303668, chr21-29304154-29305335, chr21-29305747-29309169, chr21-29313792-29314472, chr21-29315462-29315610, chr21-29315990-29317552, chr21-29318199-29318712, chr21-29319627-29319847, chr21-29320109-29320295, chr21-29320703-29320863, chr21-29321259-29321494, chr21-29321914-29322368, chr21-29322647-29323646, chr21-29323911-29324647, chr21-29324965-29325251, chr21-29327253-29327738, chr21-29329533-29331103, chr21-29331917-29333531, chr21-29334032-29336486, chr21-29336792-29337311, chr21-29337668-29337930, chr21-29339151-29339890, chr21-29340708-29341150, chr21-29341735-29344513, chr21-29345772-29351015, chr21-29351420-29352466, chr21-29352759-29353073, chr21-29354819-29355356, chr21-29356096-29358712, chr21-29359610-29363005, chr21-29365312-29366158, chr21-29367279-29367632, chr21-29368384-29387783, chr21-29389743-29390744, chr21-29392252-29392879, chr21-29394941-29397193, chr21-29457390-29457655, chr21-29459661-29460114, chr21-29463783-29464015, chr21-29465600-29465837, chr21-29469142-29469499, chr21-29470559-29470708, chr21-29472555-29472793, chr21-29473888-29474622, chr21-29475468-29478798, chr21-29481578-29482796, chr21-29485004-29485661, chr21-29495641-29495966, chr21-29496266-29496695, chr21-29498142-29498791, chr21-29499024-29500817, chr21-29501105-29501997, chr21-29504406-29504779, chr21-29504996-29505264, chr21-29505770-29506068, chr21-29639308-29651372, chr21-29652623-29653297, chr21-29654700-29655747, chr21-29656026-29658007, chr21-29658295-29660604, chr21-29661789-29662394, chr21-29667605-29667982, chr21-29669366-29669693, chr21-29669973-29670688, chr21-29671768-29672148, chr21-29673085-29673417, chr21-29684505-29684809, chr21-29688617-29688835, chr21-29817400-29817925, chr21-29827930-29828093, chr21-29828792-29830452, chr21-29843651-29844212, chr21-29847336-29847578, chr21-29847880-29847942, chr21-29848227-29851703, chr21-29854684-29855206, chr21-29867790-29868026, chr21-29870913-29871168, chr21-30032176-30032527, chr21-30033467-30033926, chr21-30035043-30035297, chr21-30044217-30045461, chr21-30046773-30047436, chr21-30191933-30192080, chr21-30193663-30195325, chr21-30452170-30452755, chr21-30458021-30458348, chr21-30460297-30460641, chr21-30463194-30464181, chr21-31078642-31079257, chr21-31081209-31081500, chr21-31082992-31084009, chr21-31084776-31087917, chr21-31088221-31089142, chr21-31096520-31101905, chr21-31173153-31175305, chr21-31175520-31176738,

Co-expression with cohesin genes Rho = 0.2883 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.445
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.867
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,Keratinocytes192627,GM12892,K1,hTERT-HME1,Spleen,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,MSiPS,K-562,Naive-hESC,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,H1-Trophectoderm,SU-DHL-2,H9-hESC,KU-19-19,Primed-hESC,NCI-H1437,iPSC,Liver,ARPE-19,HCT-116,Germinal-Center-B,REC-1,Hep-G2,HT-1197,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,Brain-Pericyte,NaiveB,U-937,BMEC,HUES64,SU-DHL-4,CyT49-hESC,H1-NPC,HUVEC,HL-60,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,KBM-7,Jurkat,CC-2551,CyT49-Gut,HAP1,HFF-hTERT,MCF7-FASR

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: 4DNFIQYQWPF5, GSE95015, GSE43070, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, ENCSR794RDS, 4DNFIBN9K4V9, ENCSR852KQC, ENCSR361AYD, 4DNFIDSWKFF5, 4DNFIZ4F74QR, 4DNFI7H4II2V, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFI9VXTBE2, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, GSE99541, ENCSR668RDP, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, 4DNFIJ5DQZVK, ENCSR658RQQ, ENCSR299VMZ, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFI8Y9SRP2, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR000FDB, 4DNFI7XAZNNQ, ENCSR527RXH, GSE105028, ENCSR833CMG, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, GSE87112, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, ENCSR146FPM, 4DNFIOX3BGNE, ENCSR478BMT, GSE69643, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, 4DNFIBT4EAKN, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, ENCSR778FXH, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIT96Z365, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIBRSIPE4, 4DNFI6CWNUFL, 4DNFI5CGQ46V, 4DNFIR8OU6QJ, 4DNFIE8E4ANZ, GSE120294, GSE84022, 4DNFIPV5KFMK, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIFHU75I5, 4DNFIYD8LO9Z, ENCSR444BAR, ENCSR123UVP, 4DNFIL9M97T2, 4DNFIJBJ6QVH, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIM2BMJ33, 4DNFIX4PJKXZ, GSE165038, 4DNFIALNLR78, 4DNFIBY3UHJB, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, GSE48592, ENCSR255XYX, ENCSR404HWQ, 4DNFIE5TEYK7, ENCSR323QIP, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, ENCSR094EIC, GSE58752, ENCSR507AHE, GSE116869, 4DNFI8649RQJ, 4DNFIRZA6EV6, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFIILDWK8M, ENCSR866FWQ, 4DNFI6EIFUZI, 4DNFII6AN691, GSE131580, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, ENCSR752QCX, ENCSR128RPG, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFI8JFOAJT, 4DNFIOCW5AEM, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFIP71EWXC, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH

Cohesin-loop subunit: SMC1,CTCF,Other,Rad21

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: P3HR-1,K-562,MCF-10A,U2OS,iPSC-megakaryocytes,Keratinocytes

Cohesin-DEGs, number of studies: 9

Cohesin-DEGs, study: GSE83870,GSE140651,GSE101921,GSE119828,GSE131448,GSE89799

Cohesin-DEGs, subunit: SMC3,SA2,SMC1,Rad21,SA1,CdLS

eachgene

Deatailed information for gene ENSG00000156265