- Basic information
- CohesinDB ID: CDBP00416118
- Locus: chr21-29094711-29095387
-
Data sourse: GSE67783, GSE120943, ENCSR153HNT
-
Cell type: K-562, Monocytes, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 43%,
"5_TxWk": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: SUZ12, CHD8, BRD1, MYB, SIX2, KDM4A, CHD7, ZFX, ARNT, ASH2L, BRD4, KLF9, XBP1, NKX2-1, EZH2, GRHL3, ERG3, MYOD1, TCF12
- Target gene symbol (double-evidenced CRMs): GRIK1,BACH1,KRTAP19-1,MAP3K7CL
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
ENSG00000184351,
- Related loop:
chr21:26175000-26200000~~chr21:29075000-29100000,
chr21:29075000-29100000~~chr21:29175000-29200000,
chr21:29075000-29100000~~chr21:29200000-29225000,
chr21:29075000-29100000~~chr21:29275000-29300000,
chr21:29075000-29100000~~chr21:29325000-29350000,
chr21:29075000-29100000~~chr21:29350000-29375000,
chr21:29075000-29100000~~chr21:29375000-29400000,
chr21:29075000-29100000~~chr21:29450000-29475000,
chr21:29075000-29100000~~chr21:29475000-29500000,
chr21:29075000-29100000~~chr21:29650000-29675000,
chr21:29075000-29100000~~chr21:29825000-29850000,
chr21:29075000-29100000~~chr21:29850000-29875000,
chr21:29075000-29100000~~chr21:30025000-30050000,
chr21:29075000-29100000~~chr21:30175000-30200000,
chr21:29075000-29100000~~chr21:30450000-30475000,
chr21:29075000-29100000~~chr21:31075000-31100000,
chr21:29075000-29100000~~chr21:31175000-31200000,
chr21:29075000-29100000~~chr21:31600000-31625000,
chr21:29089019-29091765~~chr21:29347581-29349365,
chr21:29089019-29091765~~chr21:29371286-29373596,
chr21:29089019-29091765~~chr21:29375886-29377472,
chr21:29089067-29091786~~chr21:29347632-29349367,
chr21:29089067-29091786~~chr21:29371469-29373463,
chr21:29089072-29091405~~chr21:29347617-29349359,
chr21:29089072-29091405~~chr21:29371501-29373446,
chr21:29089072-29091405~~chr21:29375869-29377598,
chr21:29089074-29091748~~chr21:29371374-29374062,
chr21:29089074-29091748~~chr21:29498802-29501235,
chr21:29089111-29092269~~chr21:29162377-29165492,
chr21:29089111-29092269~~chr21:29371324-29373748,
chr21:29089114-29093454~~chr21:29371506-29373246,
chr21:29089114-29093454~~chr21:29848944-29851080,
chr21:29089160-29091117~~chr21:29347755-29349310,
chr21:29089167-29091099~~chr21:29347660-29349347,
chr21:29089167-29091099~~chr21:29371593-29373231,
chr21:29089176-29092126~~chr21:29371501-29373493,
chr21:29089188-29091090~~chr21:29347684-29349339,
chr21:29089188-29091090~~chr21:29371617-29373249,
chr21:29089226-29091194~~chr21:29297826-29300567,
chr21:29089226-29091194~~chr21:29347657-29349380,
chr21:29089226-29091194~~chr21:29371464-29373421,
chr21:29089235-29091115~~chr21:29371527-29373259,
chr21:29089236-29091115~~chr21:29347637-29349372,
chr21:29089236-29091115~~chr21:29371371-29373442,
chr21:29089236-29091115~~chr21:29376002-29377492,
chr21:29089247-29091085~~chr21:29347692-29349326,
chr21:29089247-29091085~~chr21:29371509-29373661,
chr21:29089253-29091784~~chr21:29347649-29349937,
chr21:29089253-29091784~~chr21:29371510-29373232,
chr21:29089253-29091784~~chr21:29848754-29850764,
chr21:29089253-29091866~~chr21:29347600-29349350,
chr21:29089253-29091866~~chr21:29371097-29373582,
chr21:29089253-29091866~~chr21:29848870-29851001,
chr21:29089261-29091354~~chr21:29347652-29349375,
chr21:29089261-29091354~~chr21:29371626-29373446,
chr21:29089268-29091194~~chr21:29371479-29373222,
chr21:29089274-29091757~~chr21:29154966-29156491,
chr21:29089274-29091757~~chr21:29347569-29349367,
chr21:29089274-29091757~~chr21:29371508-29373478,
chr21:29089274-29091757~~chr21:29376083-29377369,
chr21:29089276-29091151~~chr21:29376019-29377284,
chr21:29089285-29091336~~chr21:29371361-29373472,
chr21:29089285-29091336~~chr21:29375870-29377544,
chr21:29089288-29091868~~chr21:29347684-29349364,
chr21:29089288-29091868~~chr21:29371371-29373773,
chr21:29089289-29091023~~chr21:29371556-29373423,
chr21:29089299-29091014~~chr21:29347749-29349306,
chr21:29089299-29091014~~chr21:29371547-29373219,
chr21:29089315-29091812~~chr21:29347653-29349368,
chr21:29089315-29091812~~chr21:29371099-29373462,
chr21:29089315-29091812~~chr21:29848836-29851040,
chr21:29089318-29091030~~chr21:29371154-29373646,
chr21:29089318-29091030~~chr21:29848795-29851163,
chr21:29089325-29091118~~chr21:29297646-29300784,
chr21:29089325-29091118~~chr21:29371520-29373447,
chr21:29089332-29090990~~chr21:29347656-29349372,
chr21:29089342-29090961~~chr21:29371508-29373470,
chr21:29089342-29090961~~chr21:29848928-29850617,
chr21:29089350-29091002~~chr21:29347655-29349349,
chr21:29089350-29091002~~chr21:29371542-29373242,
chr21:29089350-29091002~~chr21:29375981-29377512,
chr21:29089353-29091857~~chr21:29347586-29349777,
chr21:29089353-29091857~~chr21:29371396-29373685,
chr21:29089353-29091857~~chr21:29848791-29850711,
chr21:29089357-29091053~~chr21:29371872-29373227,
chr21:29089357-29091411~~chr21:29371472-29373597,
chr21:29089362-29091799~~chr21:29347653-29349341,
chr21:29089362-29091799~~chr21:29371531-29373749,
chr21:29089364-29091181~~chr21:29347677-29349847,
chr21:29089364-29091181~~chr21:29371607-29373564,
chr21:29089367-29091075~~chr21:29371582-29373416,
chr21:29089371-29091099~~chr21:29376007-29377431,
chr21:29089373-29091018~~chr21:29371649-29373205,
chr21:29089382-29091075~~chr21:29347811-29349358,
chr21:29089382-29091075~~chr21:29371610-29373477,
chr21:29089399-29090966~~chr21:29371712-29373257,
chr21:29089465-29091193~~chr21:29371415-29373460,
chr21:29089465-29091193~~chr21:29375968-29377586,
chr21:29089465-29091193~~chr21:29848936-29850979,
chr21:29089473-29091038~~chr21:29816962-29818235,
chr21:29089480-29091819~~chr21:29371612-29373705,
chr21:29089486-29091829~~chr21:29347582-29349316,
chr21:29089486-29091829~~chr21:29370899-29373222,
chr21:29089486-29091829~~chr21:29376085-29377438,
chr21:29089487-29090876~~chr21:29371623-29373660,
chr21:29089487-29090877~~chr21:29371648-29373217,
chr21:29089489-29091865~~chr21:29371051-29373223,
chr21:29089489-29091865~~chr21:29376014-29377430,
chr21:29089501-29091781~~chr21:29371568-29373196,
chr21:29089504-29091807~~chr21:29371508-29373687,
chr21:29089514-29090878~~chr21:29371661-29373191,
chr21:29089517-29091127~~chr21:29371534-29373393,
chr21:29089531-29090868~~chr21:29371644-29373204,
chr21:29089531-29091070~~chr21:29347741-29349366,
chr21:29089531-29091070~~chr21:29371617-29373218,
chr21:29089571-29090843~~chr21:29371675-29373153,
chr21:29089580-29091034~~chr21:29347821-29349746,
chr21:29091949-29093553~~chr21:29347639-29349364,
chr21:29091975-29093600~~chr21:29162298-29165502,
chr21:29091975-29093600~~chr21:29347653-29349368,
chr21:29091975-29093600~~chr21:29371099-29373462,
chr21:29092025-29093652~~chr21:29371361-29373472,
chr21:29092025-29093652~~chr21:29375870-29377544,
chr21:29092027-29093559~~chr21:29371542-29373242,
chr21:29092103-29093370~~chr21:29347649-29349937,
chr21:29092120-29093357~~chr21:29370899-29373222,
chr21:29100000-29125000~~chr21:29275000-29300000,
chr21:29100000-29125000~~chr21:29350000-29375000,
chr21:29100000-29125000~~chr21:29675000-29700000,
chr21:29100000-29125000~~chr21:29825000-29850000,
chr21:29100000-29125000~~chr21:29850000-29875000,
chr21:29100000-29125000~~chr21:31075000-31100000,