Deatailed information for gene ENSG00000184351
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00015700
- Gene Symbol: KRTAP19-1
- Ensembl ID: ENSG00000184351
-
Gene locus: chr21:30479705-30480367
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction
- Regulatory cohesin (double-evidenced):
chr21-29074884-29075433,
chr21-29075829-29075966,
chr21-29076222-29078000,
chr21-29079180-29079737,
chr21-29080209-29080956,
chr21-29081224-29081617,
chr21-29087569-29094441,
chr21-29094711-29095387,
chr21-29095862-29096053,
chr21-29096546-29097199,
chr21-29098256-29099251,
chr21-29099455-29101135,
chr21-30334586-30334686,
chr21-30340219-30341812,
chr21-30345002-30345474,
chr21-30348147-30348957,
chr21-30371698-30372191,
chr21-30374428-30374483,
chr21-30374805-30375152,
chr21-30484012-30484413,
chr21-30752568-30752711,
chr21-30770828-30771427,
chr21-30825036-30825632,
chr21-30826842-30827333,
chr21-30830980-30832249,
chr21-30838194-30839861,
chr21-30843090-30843297,
chr21-30844307-30844621,
chr21-30847638-30847960,
chr21-31078642-31079257,
chr21-31081209-31081500,
chr21-31082992-31084009,
chr21-31084776-31087917,
chr21-31088221-31089142,
chr21-31096520-31101905,
-
Co-expression with cohesin genes Rho = -0.0335
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.981
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.830
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: Liver,H1-hESC,HCC1599,Motor-Neuron,HFFc6,H9-hESC
- Related loop:
chr21:29075000-29100000~~chr21:30450000-30475000,
chr21:30325000-30350000~~chr21:30450000-30475000,
chr21:30350000-30375000~~chr21:30475000-30500000,
chr21:30450000-30475000~~chr21:30750000-30775000,
chr21:30450000-30475000~~chr21:30825000-30850000,
chr21:30475000-30500000~~chr21:31075000-31100000,
- Cohesin-loop type: HiChIP,HiC,Direct
- Cohesin-loop study:
4DNFIE8T8JZ8, Direct, 4DNFIMROE6N4, ENCSR094EIC, GSE105028, 4DNFI5SUHCGZ, GSE58752, GSE116872, 4DNFII84FBKM, 4DNFIILDWK8M, 4DNFI8JFOAJT
- Cohesin-loop subunit: SMC1,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: False
-
Involved cell types for DEG evidence: Keratinocytes
- Cohesin-DEGs, number of studies: 2
- Cohesin-DEGs, study: GSE83870
- Cohesin-DEGs, subunit: SMC1,SMC3