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Basic information

CohesinDB ID: CDBP00416114

Locus: chr21-29079180-29079737

Data sourse: GSE98367, GSE206145, GSE101921, GSE120943, ENCSR153HNT, GSE55407

Cell type: RPE, Monocytes, HCAEC, K-562, THP-1, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: Mau2,SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 72% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "7_Enh": 41%, "15_Quies": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, HMG20A, ZNF660, SOX2, XBP1, PATZ1, FOXA1, HDGF, NFIC, ZFP64, CTCFL, RUNX3, CHD7, ZBTB44, MORC2, MECOM, PAX5, ZSCAN4, MYOG, JMJD1C, MAF, ELF1, TRIM28, TEAD1, ZNF629, LMO2, ESR1, OCA2, MLL, USF2, ZNF561, CTCF, TCF12, JUN, KLF1, LMO1, ZBTB20, DPF2, TRIM24, IRF4, RFX5, RAD51, ZNF528, SMC1, TEAD4, KMT2B, RBPJ, EED, POU2F2, CHD8, MYCN, BRD3, RUNX1T1, CDK7, TOP2A, MTA2, ZBTB17, DUX4, ZBTB48, STAT1, ZSCAN5A, ZSCAN21, MLLT3, GATAD1, SRF, NBN, ERG, ZBTB21, PBX1, ETS1, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, GABPA, XRCC5, IKZF1, NFE2, NR2F6, ZNF639, VDR, ARNTL, NR3C1, CEBPB, KMT2A, CREB1, EZH2, KLF8, GRHL2, MRTFA, ZHX2, SPI1, GATA2, INTS13, ZNF644, GATAD2B, FLI1, SMARCA5, RELB, MRTFB, ZIM3, ZNF76, ETV5, RUNX1, BCL6, SMC1A, CEBPA, NKX2-2, ZNF335, ZFX, POU4F2, TRIM22, SMARCC1, ZNF549, PRDM10, RARA, ZNF35, RUNX2, OSR2, ZNF184, PBX4, ARNT, NFIB, DAXX, ZNF518A, ZEB2, ZNF10, FOS, CDK8, MED1, SPDEF, ZXDB, MYB, SCRT2, ZNF558, SMAD1, KLF9, EVI1, STAT5A, MAFK, BCL11A, SP1, USF1, NR4A1, ZNF317, ZBTB7A, PHIP, TCF3, PRDM6, SMC3, MLLT1, ZNF394, NFATC3, SKI, MEF2B, PPARG, ZNF207, FOXA2, EBF1, CREM, SS18, ZNF600, ZNF692, GTF2B, MEF2C, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, TCF4, HIF1A, SKIL, GATA3, BATF, TAL1, MAX, SPIB, ZNF143, GATA1, ZNF592, SP7, TCF7L2, NR2F1, ZNF687, PKNOX1, MED, NFKB1, MYOD1, ZSCAN22, BRD2, TBX21, BHLHE40, PAX3-FOXO1, AR, ZNF324, ZNF366, ZBTB26, NOTCH3, BRD4, JUND, CLOCK, MAZ, ZSCAN23, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): GRIK1,BACH1,KRTAP19-1,MAP3K7CL

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000156265, ENSG00000156273, ENSG00000171189, ENSG00000184351,

eachgene

Deatailed information for cohesin site CDBP00416114