- Basic information
- CohesinDB ID: CDBP00416128
- Locus: chr21-29121756-29123302
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Data sourse: ENCSR000DZP, GSE86191, GSE206145, ENCSR000BMY, ENCSR153HNT, GSE50893
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Cell type: RPE, GM2630, HCT-116, GM12878, GM2588, GM19238, K-562
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFATC3, FOXO1, POU2F2, MEF2B, BCL6, POU5F1, KDM4C, ZFX, MTA2, GTF2B, WT1, ZBTB48, FOXA1, SUZ12, NBN, YY1, RELA, CREBBP, TARDBP, HDGF, NFKB2, MYC, CDK6, RUNX3, SP140, ARNT, SKIL, GRHL3, HIF1A, CBFB, BATF, STAT3, MAX, PBX3, PAX5, ZNF143, IKZF1, ZEB1, ELF1, BCLAF1, KMT2A, TFAP2C, EZH2, ZNF687, PKNOX1, OCA2, NFKB1, CTCF, TCF12, SND1, SPI1, ARRB1, TBX21, BHLHE40, GSPT2, TAF1, PAX8, POU2F3, ASH2L, IKZF2, BRD4, SMARCA5, BCOR, HNRNPLL, RELB, MAZ, SMC3, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): BACH1,GRIK1,MAP3K7CL
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 56
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:29100000-29125000~~chr21:29275000-29300000,
chr21:29100000-29125000~~chr21:29350000-29375000,
chr21:29100000-29125000~~chr21:29675000-29700000,
chr21:29100000-29125000~~chr21:29825000-29850000,
chr21:29100000-29125000~~chr21:29850000-29875000,
chr21:29100000-29125000~~chr21:31075000-31100000,
chr21:29124718-29126312~~chr21:29176363-29177502,