- Basic information
- CohesinDB ID: CDBP00416129
- Locus: chr21-29124971-29125928
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Data sourse: GSE93080, ENCSR000EAC, ENCSR000DZP, GSE85526, ENCSR000BMY, GSE50893
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Cell type: GM12892, GM2630, SNYDER, HEKn, GM2610, GM19240, GM12878, GM12891, GM2588, GM12890, GM19238, GM19099, GM2255, GM19239, GM18951, GM18486
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 84%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA1, NFIC, RUNX3, CBFB, MECOM, PAX5, ZNF287, BCLAF1, MLL, OCA2, CTCF, TCF12, DPF2, RAD51, EED, POU2F2, CDK7, MTA2, DDX5, NBN, ARID3A, ERG, MYC, RAD21, GRHL3, STAT3, IKZF1, KMT2A, SPI1, GATA2, ZNF644, ZNF777, SMARCA5, RELB, RUNX1, BCL6, SMC1A, ZFX, TRIM22, PRDM10, MEF2A, CREBBP, ZNF384, ZBTB2, GATA4, ARNT, ATF2, ETV6, PBX3, CDK8, MED1, MYB, PIAS1, BCL11A, ATF7, ASH2L, TCF3, BCOR, MLLT1, NFATC3, MEF2B, FOXA2, ZNF207, EBF1, GTF2B, YY1, RELA, TARDBP, JUNB, TCF4, SKIL, HIF1A, GATA3, BATF, NR2F1, PKNOX1, MED, TBX21, BHLHE40, ZNF445, ZBTB40, RNF2, IKZF2, BRD4, ZNF24
- Target gene symbol (double-evidenced CRMs): BACH1,GRIK1,MAP3K7CL
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 28
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:29100000-29125000~~chr21:29275000-29300000,
chr21:29100000-29125000~~chr21:29350000-29375000,
chr21:29100000-29125000~~chr21:29675000-29700000,
chr21:29100000-29125000~~chr21:29825000-29850000,
chr21:29100000-29125000~~chr21:29850000-29875000,
chr21:29100000-29125000~~chr21:31075000-31100000,
chr21:29124718-29126312~~chr21:29176363-29177502,