Deatailed information for cohesin site CDBP00416136


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  • Basic information
  • CohesinDB ID: CDBP00416136
  • Locus: chr21-29148256-29148957
  • Data sourse: ENCSR000DZP, GSE111537, ENCSR000BLY, ShirahigeLab, GSE101921, ShirahigeLab-NatGen2015, GSE116344, GSE50893, GSE165895
  • Cell type: RPE, HMEC, Fibroblast, RH4, GM12878, GM19238, SK-N-SH, GM19239, OCI-AML-3, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 4% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.889
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 43%, "7_Enh": 24%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, PGR, SOX2, XBP1, FOXA1, BMI1, NFIC, RUNX3, CBFB, PAX5, MAF, JMJD1C, ELF1, TRIM28, ZNF217, ESR1, TP73, CTCF, TCF12, LMO1, DPF2, TRIM24, SMC1, RBPJ, EED, POU2F2, CHD8, MYCN, TOP2A, CDK7, RUNX1T1, MTA2, NBN, ZNF300, ERG, MYC, SMARCA4, GRHL3, BATF3, GABPA, IKZF1, ARNTL, NR3C1, CEBPB, STAT5B, KMT2A, EZH2, ZHX2, SPI1, RELB, RUNX1, BCL6, CEBPA, ZFX, SMARCC1, PRDM10, CREBBP, RUNX2, ARNT, HMGB2, SUPT5H, CDK8, MED1, MYB, STAT5A, BCL11A, ATF7, TCF3, MLLT1, NFATC3, EBF1, MEIS1, SS18, CDK9, RELA, TARDBP, TCF4, HIF1A, SKIL, GATA3, BATF, TAL1, MAX, BCL11B, NCOA3, NEUROG2, NR2F1, MED, ZNF334, NFKB1, MYOD1, TBX21, BHLHE40, AR, IKZF2, BRD4, ZNF24
  • Target gene symbol (double-evidenced CRMs): MAP3K7CL
  • Function elements
  • Human SNPs: Height
  • Number of somatic mutations (coding): 30
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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