- Basic information
- CohesinDB ID: CDBP00416137
- Locus: chr21-29150671-29151440
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Data sourse: GSE206145, GSE126755, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, RPE, Neutrophil
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, POU5F1, SS18, SMAD3, FOXA1, HOXB13, SMARCC1, HNF4G, ERG, RELA, NFIC, RUNX2, BRG1, ARNT, HIF1A, GATA3, PRDM9, GABPA, STAT3, APC, NKX3-1, FOS, GATA1, CHD1, ARNTL, NR3C1, CEBPB, NCOA3, TEAD1, CREB1, PIAS1, ZNF331, EZH2, ESR1, MED26, GRHL2, ZNF334, MYOD1, JUN, TCF12, CTCF, BAF155, BCL11A, AR, GATA2, BRD4, ZIM3
- Target gene symbol (double-evidenced CRMs): BACH1,GRIK1,MAP3K7CL
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:29089274-29091757~~chr21:29154966-29156491,
chr21:29150000-29175000~~chr21:29275000-29300000,
chr21:29150000-29175000~~chr21:29325000-29350000,
chr21:29150000-29175000~~chr21:29350000-29375000,
chr21:29150000-29175000~~chr21:29475000-29500000,
chr21:29150000-29175000~~chr21:29825000-29850000,
chr21:29150000-29175000~~chr21:30175000-30200000,