- Basic information
- CohesinDB ID: CDBP00416138
- Locus: chr21-29152909-29153775
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Data sourse: GSE206145, ENCSR153HNT, GSE98367
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Cell type: K-562, RPE, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, FOXO1, PGR, FOXA2, POU5F1, CEBPA, SS18, ZNF335, SOX2, ZNF692, ZBTB17, FOXA1, HOXB13, SMARCC1, PRDM10, RELA, ZNF384, ZNF35, OGG1, MYC, GATA4, SMARCA4, OSR2, SOX11, GATA3, GABPA, STAT3, TP63, GATA1, FOS, MED1, CBX2, NR3C1, CEBPB, NR2F2, TP53, TP73, TBX5, JUN, AR, NKX2-5, GATA2, FLI1, RNF2, BRD4, PRDM6
- Target gene symbol (double-evidenced CRMs): BACH1,MAP3K7CL,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 70
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:29089274-29091757~~chr21:29154966-29156491,
chr21:29150000-29175000~~chr21:29275000-29300000,
chr21:29150000-29175000~~chr21:29325000-29350000,
chr21:29150000-29175000~~chr21:29350000-29375000,
chr21:29150000-29175000~~chr21:29475000-29500000,
chr21:29150000-29175000~~chr21:29825000-29850000,
chr21:29150000-29175000~~chr21:30175000-30200000,