Deatailed information for cohesin site CDBP00416139

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  • Basic information
  • CohesinDB ID: CDBP00416139
  • Locus: chr21-29155290-29156050
  • Data sourse: ENCSR000BLD, ENCSR230ZWH, ENCSR000BLY, GSE105028, GSE103477, GSE131606, GSE25021, GSE165895, ENCSR000EFJ, GSE67783, ENCSR000BKV, GSE86191, GSE101921, GSE206145-NatGen2015, GSE120943, GSE130135, ENCSR703TNG, GSE94872, GSE98367, ENCSR879KXD, ENCSR000EHW, GSE206145, ENCSR000EHX, GSE97394, GSE111913, ENCSR153HNT, GSE68388, GSE50893, GSE126755
  • Cell type: MDM, GM2610, Liver, HuCC-T1, H9-hESC, RPE, Fibroblast, IMR-90, K-562, DKO, HFFc6, H1-hESC, Monocytes, SK-N-SH, RT-112, Macrophage, HUES64, MCF-7, HCT-116, HEK293T, HUVEC, HCAEC, Neutrophil, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 11% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.722
  • Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 72% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 29%, "1_TssA": 19%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: PGR, ZNF660, ZSCAN5C, XBP1, PATZ1, FOXA1, PBX2, UBTF, ZFHX2, ATF3, ZFP64, PRDM1, IKZF3, CBFB, ZNF189, MECOM, TP63, ZNF467, ZNF629, JMJD1C, TEAD1, TRIM28, ZNF573, ETV1, ELF1, ESR1, MED26, ZNF561, CTCF, TCF12, JUN, KLF1, ZBTB20, GATA6, E2F6, SOX6, E2F1, ZNF528, SMC1, ZNF280A, TEAD4, TFAP2C, EED, GLIS1, CHD8, BRD3, ZNF263, POU5F1, KDM4C, MYCN, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ID3, STAT1, SRF, BAHD1, ERG2, SP4, TBP, ERG, ZBTB21, HOXC5, ZNF341, ZBTB8A, MYC, ETS1, SMARCA4, ARID1B, RAD21, GRHL3, ZNF398, IKZF1, RCOR1, HNRNPH1, ZNF639, NR3C1, CEBPB, ZNF750, KMT2A, ZBTB11, KLF8, EBF3, SPI1, ZNF664, EHF, ZNF257, HDAC2, GATA2, MXD3, ZNF146, FLI1, MRTFB, ZNF76, ZNF554, ATF1, ETV5, RUNX1, ZNF585A, SMC1A, CBX1, HDAC1, CEBPA, ZNF335, SIN3A, ZNF534, SMAD3, TET2, CBX8, ERG3, ZNF513, SMARCC1, PRDM10, ZNF549, CREBBP, ZNF384, CBX4, ZNF35, ZNF133, RUNX2, SMAD2, GATA4, OSR2, ZNF184, ZSCAN30, SP3, PBX4, ZBTB10, ZNF48, ZEB2, ZNF518A, CBFA2T3, PBX3, SP2, ZNF10, CDK8, MED1, TEAD3, CEBPD, ZXDB, ZNF558, L3MBTL2, SETDB1, KLF16, BCL11A, REST, ATF7, PHIP, BCOR, GLIS2, AFF1, SMC3, STAG1, ZNF394, NFATC3, PPARG, FOXA2, TBL1X, MTA3, CBX3, SS18, CREM, ZNF600, ZNF692, WT1, ZNF574, ZNF580, YY1, RELA, ZNF610, ZFP36, ZIC2, HIF1A, SKIL, GATA3, MGA, TAL1, MAX, ZNF449, GATA1, ZNF143, CBX2, CEBPG, ZFP69B, SP7, NCOA3, KLF4, GFI1B, NR2F1, ZNF768, TP53, ZBTB6, ZSCAN22, MYOD1, ZNF140, PHOX2B, BRD2, EGR2, AR, PAX3-FOXO1, TAF1, RXR, ZNF324, ZNF366, EGR1, ZBTB42, RNF2, NOTCH3, BRD4, JUND, MAZ, ZNF24
  • Target gene symbol (double-evidenced CRMs): BACH1,GRIK1,MAP3K7CL
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000156265, ENSG00000156273, ENSG00000171189,
  • Related loop: chr21:29089274-29091757~~chr21:29154966-29156491, chr21:29150000-29175000~~chr21:29275000-29300000, chr21:29150000-29175000~~chr21:29325000-29350000, chr21:29150000-29175000~~chr21:29350000-29375000, chr21:29150000-29175000~~chr21:29475000-29500000, chr21:29150000-29175000~~chr21:29825000-29850000, chr21:29150000-29175000~~chr21:30175000-30200000,
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