- Basic information
- CohesinDB ID: CDBP00416141
- Locus: chr21-29159810-29160209
-
Data sourse: GSE120943, ENCSR153HNT, GSE98367
-
Cell type: K-562, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 59%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RELA, CHD8, BRD1, RUNX2, ZEB1, TOP2A, EZH2, XBP1, ZNF3, OCA2, CTCF, STAT1, CLOCK, JUN, ZNF143, SPI1
- Target gene symbol (double-evidenced CRMs): BACH1,MAP3K7CL,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 270
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156265,
ENSG00000156273,
ENSG00000171189,
- Related loop:
chr21:29089111-29092269~~chr21:29162377-29165492,
chr21:29089274-29091757~~chr21:29154966-29156491,
chr21:29091975-29093600~~chr21:29162298-29165502,
chr21:29150000-29175000~~chr21:29275000-29300000,
chr21:29150000-29175000~~chr21:29325000-29350000,
chr21:29150000-29175000~~chr21:29350000-29375000,
chr21:29150000-29175000~~chr21:29475000-29500000,
chr21:29150000-29175000~~chr21:29825000-29850000,
chr21:29150000-29175000~~chr21:30175000-30200000,
chr21:29162246-29165257~~chr21:29217358-29218786,
chr21:29162298-29165502~~chr21:29297765-29300738,
chr21:29162305-29165453~~chr21:29297767-29300990,
chr21:29162305-29165453~~chr21:29347649-29349937,
chr21:29162305-29165453~~chr21:29371510-29373232,
chr21:29162307-29165517~~chr21:29297019-29300536,
chr21:29162307-29165517~~chr21:29371097-29373582,
chr21:29162310-29165464~~chr21:29297711-29300996,
chr21:29162310-29165464~~chr21:29371472-29373597,
chr21:29162316-29165407~~chr21:29347639-29349336,
chr21:29162316-29165407~~chr21:29371587-29373476,
chr21:29162347-29165506~~chr21:29347569-29349367,
chr21:29162347-29165506~~chr21:29371508-29373478,
chr21:29162377-29165492~~chr21:29297770-29301094,
chr21:29162377-29165492~~chr21:29371324-29373748,
chr21:29162378-29165498~~chr21:29297718-29300698,
chr21:29162378-29165498~~chr21:29347586-29349777,
chr21:29162378-29165498~~chr21:29371396-29373685,
chr21:29162871-29165217~~chr21:29297676-29300550,
chr21:29162871-29165217~~chr21:29371415-29373460,
chr21:29162973-29165491~~chr21:29371374-29374062,
chr21:29163076-29165466~~chr21:29371531-29373749,
chr21:29163267-29165505~~chr21:29371371-29373442,
chr21:29163284-29165488~~chr21:29347632-29349367,
chr21:29163284-29165488~~chr21:29371469-29373463,
chr21:29163305-29165274~~chr21:29297780-29300635,
chr21:29163327-29165509~~chr21:29371286-29373596,
chr21:29163333-29165304~~chr21:29297741-29300792,
chr21:29163333-29165304~~chr21:29347811-29349358,
chr21:29163334-29165506~~chr21:29371501-29373446,
chr21:29163344-29165555~~chr21:29371154-29373646,
chr21:29163366-29165439~~chr21:29371508-29373470,
chr21:29163425-29165457~~chr21:29371556-29373423,
chr21:29163439-29165245~~chr21:29347811-29349339,
chr21:29163441-29165302~~chr21:29371582-29373416,
chr21:29163452-29165270~~chr21:29371509-29373661,
chr21:29163509-29165242~~chr21:29347678-29349344,
chr21:29163629-29165264~~chr21:29297785-29301017,
chr21:29163629-29165264~~chr21:29347677-29349365,
chr21:29163690-29165671~~chr21:29370899-29373222,
chr21:29163705-29165544~~chr21:29371661-29373191,
chr21:29163714-29165477~~chr21:29347632-29349309,
chr21:29163714-29165477~~chr21:29371612-29373705,
chr21:29163723-29165657~~chr21:29371051-29373223,
chr21:29163725-29165459~~chr21:29347656-29349372,
chr21:29163734-29165276~~chr21:29347684-29349339,
chr21:29163746-29165675~~chr21:29347638-29349313,
chr21:29163746-29165675~~chr21:29371508-29373687,
chr21:29163756-29165286~~chr21:29347699-29349347,
chr21:29163791-29165490~~chr21:29371644-29373204,
chr21:29163801-29165267~~chr21:29347792-29349359,
chr21:29163801-29165269~~chr21:29347138-29349317,
chr21:29163806-29165395~~chr21:29499245-29500556,
chr21:29163806-29165395~~chr21:29848934-29850864,