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Basic information

CohesinDB ID: CDBP00416246

Locus: chr21-29501105-29501997

Data sourse: ENCSR000EFJ, GSE206145, GSE206145-NatGen2015, GSE135093, GSE165895

Cell type: RPE, Fibroblast, IMR-90, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 37% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 77%, "5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, FOXA2, SOX2, SMARCC1, RELA, JUNB, MYC, DAXX, FOS, RCOR1, MED1, NR3C1, CEBPB, NR2F2, NFKB1, BHLHE40, AR, GATA2, BRD4, FOSL2

Target gene symbol (double-evidenced CRMs): MAP3K7CL,GRIK1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000156265, ENSG00000171189,

eachgene

Deatailed information for cohesin site CDBP00416246