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Basic information

CohesinDB ID: CDBP00416308

Locus: chr21-29817400-29817925

Data sourse: ENCSR000BLD, ENCSR000EAC, GSE143937, ENCSR230ZWH, ENCSR000BKV, GSE25021, ENCSR000BLY, GSE105028, ENCSR000ECE, ENCSR000BMY, ENCSR000EDE, GSE68388, GSE106870, GSE50893, GSE97394, ENCSR917QNE

Cell type: GM2610, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, HeLa-S3, K-562, H1-hESC, GM12878, GM12891, GM2588, SK-N-SH, HUES64, MCF-7, GM12892, GM19238

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.789

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 28% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 87%, "14_ReprPCWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CHD8, FOXA2, SOX2, XBP1, FOXA1, ZBTB33, CDK9, PBX2, ZKSCAN1, ERG, YY1, RELA, ZBTB2, KDM1A, MYC, ONECUT1, RAD21, HIF1A, RXRA, GATA3, PRDM9, MAX, IKZF1, NFE2, RCOR1, NR2F6, TLE3, NR3C1, GFI1B, ZNF573, PIAS1, EZH2, LMO2, ESR1, C11orf30, CTCF, USF1, BAF155, SP1, HNF4A, AR, HDAC2, GATA2, ZNF777, E2F1, STAG1, ZNF316

Target gene symbol (double-evidenced CRMs): TIAM1,GRIK1,MAP3K7CL,BACH1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 14

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156265, ENSG00000156273, ENSG00000171189, ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416308