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Basic information

CohesinDB ID: CDBP00416369

Locus: chr21-30348147-30348957

Data sourse: GSE67783, GSE86191, GSE98367, GSE206145-NatGen2015, GSE120943

Cell type: Fibroblast, HCT-116, Monocytes, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 22% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 80%, "9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, PPARG, FOXA2, ZNF263, CRY1, TOP2A, NME2, SOX2, XBP1, ZBTB48, WT1, FOXA1, HOXB13, ERG, KDM1A, RELA, YY1, JUNB, RFX1, CHD7, DAXX, PBX4, RXRA, MAX, NKX3-1, ZNF143, FOS, TLE3, PDX1, TEAD1, PIAS1, OCA2, SETDB1, CTCF, T, JUN, BAF155, EP300, AR, GATA2, SIX2, FLI1, HSF1, ASH2L, ZBTB26, BRD4, FOXP1, HCFC1R1, SMC3, STAG1

Target gene symbol (double-evidenced CRMs): KRTAP19-1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 57

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene: ENSG00000184351,

eachgene

Deatailed information for cohesin site CDBP00416369