- Basic information
- CohesinDB ID: CDBP00416437
- Locus: chr21-30838194-30839861
-
Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE116868, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, ENCSR000BKV, GSE122299, GSE138405, GSE86191, GSE76893, GSE101921, ENCSR198ZYJ, GSE138105, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, ENCSR000EEG, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE131956, GSE129526, GSE111913, GSE155324, GSE38411, ENCSR000EDE, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
-
Cell type: RH4, GM2610, SLK, CVB-hiPSC, GM19240, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, HMEC, HEKn, Ishikawa, GM12890, HeLa-S3, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, RT-112, THP-1, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, Neurons-H1, A-549, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 29% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.478
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
21% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 78%,
"9_Het": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RELA, ARNTL, AR, CEBPB, CHD8, REST, CREB1, ZFX, NRF1, XBP1, WT1, ATF2, CTCF, ZNF143, EP300
- Target gene symbol (double-evidenced CRMs): KRTAP19-1,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
ENSG00000184351,
ENSG00000156299,
- Related loop:
chr21:30340375-30341994~~chr21:30838731-30840270,
chr21:30450000-30475000~~chr21:30825000-30850000,
chr21:30505120-30506860~~chr21:30838591-30840304,
chr21:30825000-30850000~~chr21:30925000-30950000,
chr21:30825000-30850000~~chr21:31025000-31050000,
chr21:30825000-30850000~~chr21:31050000-31075000,
chr21:30825000-30850000~~chr21:31075000-31100000,
chr21:30825000-30850000~~chr21:31250000-31275000,
chr21:30825000-30850000~~chr21:31600000-31625000,
chr21:30838509-30840405~~chr21:31085305-31087770,
chr21:30838591-30840304~~chr21:31085537-31087555,
chr21:30838850-30840221~~chr21:31085886-31087793,
chr21:30838921-30840264~~chr21:31603607-31605876,