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Basic information

CohesinDB ID: CDBP00413613

Locus: chr21-15891358-15891425

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 58% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 80%, "5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, ZNF426, PGR, ZNF496, XBP1, HNF1A, FOXA1, SUZ12, LEO1, SRSF4, ATF3, PRDM1, ATF4, MORC2, PAX5, ZSCAN4, TEAD1, SNAI2, ESR1, HNF1B, TP73, CTCF, JUN, BAF155, DPF2, E2F6, SMC1, TEAD4, TFAP2C, POU2F2, CHD8, ZSCAN5D, TOP2A, DUX4, ZSCAN5A, SRF, DDX5, ERG, MYC, SMARCA4, RAD21, GRHL3, NKX2-1, GABPA, NKX3-1, TERF2, DACH1, ARNTL, NR3C1, ESRRA, CEBPB, EZH2, GRHL2, EBF3, SPI1, IRF1, GATA2, SIX2, RUNX1, SMC1A, NKX2-2, ZFX, ZNF654, SMARCC1, ZBTB2, ZNF384, ZNF133, RUNX2, GATA4, ARNT, NRF1, ATF2, HMGB2, SUPT5H, MED1, PIAS1, C11orf30, ZNF41, L3MBTL2, ZNF22, RBM22, MAFK, BCL11A, FOXP1, SMC3, NCOR2, STAG1, STAG2, NFATC3, PPARG, FOXA2, PAF1, NFATC1, GTF2B, MAFF, FOXF1, CDK9, HOXB13, ZKSCAN1, MPHOSPH8, KDM1A, YY1, RELA, BCL3, JUNB, BRG1, ZFP36, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, AGO2, TLE3, KLF4, ZNF334, PHOX2B, T, AR, PAX3-FOXO1, NOTCH3, SCRT1, BRD4, CUX1, MAZ, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): CXADR,BTG3,HSPA13

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155304, ENSG00000154639, ENSG00000154640,

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Deatailed information for cohesin site CDBP00413613