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Basic information

CohesinDB ID: CDBP00413855

Locus: chr21-16933256-16933897

Data sourse: GSE206145-GSE177045

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 91%, "9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NANOG, CHD8, PGR, POU5F1, SOX2, SIN3A, GTF2B, ZBTB17, FOXA1, ZNF823, HOXB13, ERG, RELA, CREBBP, ZNF384, ZXDC, NEUROD1, NFIC, GATA4, EOMES, GR, RAD21, CHD7, GRHL3, HIF1A, PCGF1, ARNT, OTX2, GATA3, PRDM9, GABPA, BATF3, STAT3, SMARCE1, NKX2-1, NKX3-1, SOX11, ATF2, TLE3, NR3C1, ESRRA, TEAD1, TFAP2C, TCF7L2, CREB1, ESR1, ZNF140, TRPS1, T, TCF12, BRD2, BAF155, TFAP2A, PHOX2B, AR, IRF1, GATA6, ZNF182, ATF7, FLI1, BRD4, JUND, TEAD4, AHR

Target gene symbol (double-evidenced CRMs): CXADR,BTG3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000154639, ENSG00000154640,

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Deatailed information for cohesin site CDBP00413855