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Basic information

CohesinDB ID: CDBP00413856

Locus: chr21-16941592-16944786

Data sourse: ENCSR230ZWH, ENCSR330ELC, ENCSR000BUC, ENCSR000DYE, ENCSR917QNE, GSE115602, GSE67783, GSE86191, GSE36578, GSE101921, ENCSR806UKK, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, GSE130140, ENCSR247LSH, GSE105004, ENCSR676MJK, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE131577, GSE126634, GSE103477, GSE108869, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE111537, GSE25021, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE155828, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE68388, GSE126990

Cell type: RH4, GM2610, SLK, CVB-hiPSC, HSPC, CUTLL1, CVI-hiPSC, Liver, Transformed-RPE1, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, HEKn, Ishikawa, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, H1-hESC, SNYDER, MB157, GM12878, GM12891, GM2588, GBM39, HUES9, SK-N-SH, RT-112, HeLa-Tet-On, THP-1, HUES64, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, HeLa, BGO3, TC-71, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 46% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.456

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 80%, "9_Het": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF384, ZNF317, BRD4, ZNF136, CTCF

Target gene symbol (double-evidenced CRMs): BTG3,CXADR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 22

Related genes and loops

Related gene: ENSG00000154639, ENSG00000154640,

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Deatailed information for cohesin site CDBP00413856