- Basic information
- CohesinDB ID: CDBP00415216
- Locus: chr21-25387847-25388717
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Data sourse: GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR000BMY, ENCSR153HNT, GSE50893
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Cell type: RPE, Fibroblast, SNYDER, GM12878, GM2588, K-562, GM19239, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 84%,
"14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, POU5F1, TOP2A, ZFX, POU4F2, XBP1, ERG, YY1, RELA, MYC, GRHL3, ARNT, RXRA, GATA1, ZEB1, CREB1, OCA2, SETDB1, CTCF, NOTCH3, BRD4, EED
- Target gene symbol (double-evidenced CRMs): GABPA,ATP5PF,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154723,
ENSG00000154727,
ENSG00000154734,
- Related loop:
chr21:18275000-18300000~~chr21:25375000-25400000,
chr21:21000000-21025000~~chr21:25375000-25400000,
chr21:21150000-21175000~~chr21:25375000-25400000,
chr21:22350000-22375000~~chr21:25375000-25400000,
chr21:23125000-23150000~~chr21:25375000-25400000,
chr21:24513423-24515010~~chr21:25384975-25387237,
chr21:24513697-24514874~~chr21:25385247-25387032,
chr21:24550000-24575000~~chr21:25375000-25400000,
chr21:24875000-24900000~~chr21:25375000-25400000,
chr21:24894830-24897390~~chr21:25384467-25387269,
chr21:24894830-24897394~~chr21:25385024-25387052,
chr21:24895217-24897409~~chr21:25384906-25387309,
chr21:24895246-24897306~~chr21:25385187-25387188,
chr21:24895257-24897346~~chr21:25384844-25387316,
chr21:24895401-24897292~~chr21:25385277-25387061,
chr21:24895404-24897444~~chr21:25384540-25387027,
chr21:24895412-24897374~~chr21:25384467-25386981,
chr21:24895417-24897339~~chr21:25385234-25387033,
chr21:24895431-24897366~~chr21:25384794-25387223,
chr21:24895435-24897297~~chr21:25385320-25387052,
chr21:24895436-24897312~~chr21:25385038-25387061,
chr21:24895454-24897362~~chr21:25385185-25387028,
chr21:24895510-24897368~~chr21:25384420-25387034,
chr21:24895582-24897226~~chr21:25384605-25386845,
chr21:24900000-24925000~~chr21:25375000-25400000,
chr21:25025000-25050000~~chr21:25375000-25400000,
chr21:25038878-25040962~~chr21:25384794-25387223,
chr21:25038960-25041269~~chr21:25384420-25387034,
chr21:25050000-25075000~~chr21:25375000-25400000,
chr21:25175000-25200000~~chr21:25375000-25400000,
chr21:25275000-25300000~~chr21:25375000-25400000,
chr21:25282035-25284813~~chr21:25385187-25387188,
chr21:25282774-25284961~~chr21:25384973-25387124,
chr21:25282884-25285002~~chr21:25384844-25387316,
chr21:25282903-25284758~~chr21:25385202-25387023,
chr21:25282928-25284802~~chr21:25384906-25387309,
chr21:25283150-25284658~~chr21:25385262-25387043,
chr21:25349142-25351714~~chr21:25384975-25387237,
chr21:25349194-25351726~~chr21:25385187-25387188,
chr21:25349223-25351193~~chr21:25385202-25387023,
chr21:25349228-25351734~~chr21:25384973-25387124,
chr21:25349249-25351723~~chr21:25385057-25387036,
chr21:25349307-25351726~~chr21:25385207-25387036,
chr21:25349328-25351256~~chr21:25385367-25387046,
chr21:25349357-25351711~~chr21:25384906-25387309,
chr21:25349579-25351235~~chr21:25385229-25387028,
chr21:25375000-25400000~~chr21:25725000-25750000,
chr21:25375000-25400000~~chr21:26825000-26850000,