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Basic information

CohesinDB ID: CDBP00415217

Locus: chr21-25395973-25396887

Data sourse: GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE155324, GSE206145, ENCSR000BMY, GSE50893

Cell type: GM12892, GM2630, SNYDER, GM10847, GM2610, Lymphoblast, GM19240, GM12878, GM12891, GM2588, GM12890, GM19238, hLCL, GM2255, GM19239, GM18486, B-cell

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.811

Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 88%, "7_Enh": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX5, XBP1, HDGF, BMI1, NFIC, RUNX3, PRDM1, CBFB, PAX5, MAF, BCLAF1, ZNF217, JUN, TCF12, CTCF, EP300, SND1, DPF2, IRF4, GTF2F1, RBPJ, EED, POU2F2, ZSCAN5D, MTA2, STAT1, SRF, NBN, ARID3A, CHD4, NFKB2, MYC, RAD21, BATF3, STAT3, IKZF1, TERF2, HNRNPH1, ARNTL, STAT5B, CREB1, EZH2, SPI1, GATAD2B, DRAP1, SMARCA5, RELB, RUNX1, SMC1A, AFF4, ZFX, TRIM22, ZNF18, MEF2A, ZBTB2, ARNT, ATF2, FOXM1, ETV6, PBX3, MED1, PML, TERF1, MYB, ZMYM3, STAT5A, BCL11A, NIPBL, SP1, REST, ATF7, ASH2L, TCF3, MLLT1, NFATC3, MEF2B, ZNF207, MTA3, EBF1, CREM, NFATC1, HDAC6, GTF2B, ZBED1, BCL3, YY1, RELA, TARDBP, JUNB, SKIL, HIF1A, BATF, MAX, ZNF143, NR2F1, ZNF687, PKNOX1, TP53, NFKB1, TBX21, BHLHE40, TAF1, EGR1, RNF2, IKZF2, BRD4, JUND, AHR

Target gene symbol (double-evidenced CRMs): ATP5PF,GABPA,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 7

Related genes and loops

Related gene: ENSG00000154723, ENSG00000154727, ENSG00000154734,

Tools:

Assay

refGene

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Cohesin site CDBP00415217

CDBP00415217 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00415217

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