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Basic information

CohesinDB ID: CDBP00415272

Locus: chr21-25626696-25627327

Data sourse: GSE206145-GSE177045, ENCSR230ZWH

Cell type: MCF-7, Liver

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 61% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 80%, "7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, NFIA, PGR, CHD8, CHD2, SOX2, FOXA1, ZNF300, ERG, RELA, CREBBP, NFIC, CDK6, SMARCA4, RUNX2, MYC, NFIB, GRHL3, GATA3, GABPA, STAT3, MAX, NRIP1, ZNF143, MED1, NR3C1, ESRRA, NR2F2, TEAD1, TCF7L2, NEUROG2, ESR1, GRHL2, EBF3, CTCF, TFAP2A, AR, GATA2, ZBTB42, ASH2L, HSF1, TFAP2C

Target gene symbol (double-evidenced CRMs): ADAMTS1,GABPA,APP,ATP5PF

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000154723, ENSG00000154727, ENSG00000142192, ENSG00000154734,

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Deatailed information for cohesin site CDBP00415272