- Basic information
- CohesinDB ID: CDBP00415288
- Locus: chr21-25699316-25700064
-
Data sourse: GSE67783, GSE86191, ShirahigeLab, ShirahigeLab-NatGen2015, GSE116344
-
Cell type: RPE, Fibroblast, RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 62%,
"5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOSL1, CEBPA, SIN3A, ZBTB48, SMAD3, STAT1, ZBTB33, HOXC5, RELA, CREBBP, ZNF384, JUNB, ATF3, RUNX2, MYC, NFIC, ZNF362, ARID1B, CHD7, GATA4, DAXX, PBX4, RXRA, GATA3, TAL1, CBFA2T3, PBX3, MAX, ZNF143, CDK8, FOS, STAT3, MED1, NR3C1, CEBPB, SMAD1, NFE2L2, MYOD1, ZNF22, JUN, TCF12, ZHX2, MAFK, EP300, SP1, BHLHE40, DPF2, BRD4, JUND, SMC3, FOSL2
- Target gene symbol (double-evidenced CRMs): JAM2,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops