Deatailed information for cohesin site CDBP00415292
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBP00415292
- Locus: chr21-25717358-25718663
- Data sourse: GSE126634, GSE152721, GSE86191
- Cell type: HCT-116, HAP1
- DNA Sequence of binding site: UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
- CTCF binding site: non-CTCF CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
- Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
- Compartment: 61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 64%,
"15_Quies": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2). - Co-bound Transcriptional factors: FOXO1, NFIA, ZNF660, SOX2, MEIS2, FOXA1, LEO1, HDGF, ATF3, NFIC, ZBTB44, ATF4, ZNF189, PAX5, NFE2L2, JUN, CTCF, GATA6, DPF2, SOX6, ZNF528, TEAD4, POU5F1, TOP2A, ZBTB17, DUX4, ZBTB48, ZSCAN5A, NBN, ARID3A, HOXC5, SMARCC2, MYC, SMARCA4, ARID1B, RAD21, GRHL3, NKX2-1, FOXK2, NFE2, CEBPB, ZNF93, ZNF664, GATA2, FLI1, NFYB, RUNX1, MAFG, HDAC1, ZFX, PRDM10, ZNF35, RUNX2, OSR2, ZNF184, PBX4, NFIB, ATF2, HMBOX1, MED1, TERF1, SCRT2, SMAD1, C11orf30, MAFK, BCL11A, ZBTB7A, ATF7, PRDM6, ZNF394, PAF1, ZNF692, MAFF, WT1, ZBTB33, CDK9, HOXB13, RELA, AHR, OTX2, TAL1, MAX, GATA1, CEBPG, NR2F2, ZNF366, JUND, ILF3, ZNF316
- Target gene symbol (double-evidenced CRMs): JAM2,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene: ENSG00000154719, ENSG00000154721,
- Related loop: chr21:25100000-25125000~~chr21:25700000-25725000, chr21:25400000-25425000~~chr21:25700000-25725000, chr21:25425000-25450000~~chr21:25700000-25725000, chr21:25450000-25475000~~chr21:25700000-25725000, chr21:25575000-25600000~~chr21:25700000-25725000, chr21:25600000-25625000~~chr21:25700000-25725000,
Tools:
- Assay
