- Basic information
- CohesinDB ID: CDBP00415318
- Locus: chr21-25846197-25846384
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Data sourse: ENCSR000BTU, GSE25021
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Cell type: MCF-7, Ishikawa
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 67%,
"14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PAX7, FOSL1, PGR, SMC1A, FOXA2, MTA3, CREM, NFATC1, ZFX, NME2, MTA2, ZBED1, DUX4, FOXA1, FOXF1, ERG3, CBX8, TCF7, ERG2, HOXB13, ERG, RELA, ZNF384, NEUROD1, JUNB, MYC, RUNX2, GATA4, NFIC, SMARCA4, RUNX3, AHR, GRHL3, ARNT, HIF1A, NKX2-1, OTX2, GATA3, BATF, GABPA, BATF3, FOXM1, ETV6, ATF2, CBFB, ZFP69B, NR2F2, TEAD1, PML, SCRT2, PIAS1, NR2F1, EZH2, ZNF217, CREB1, ETV1, NEUROG2, EGR2, STAT5A, CTCF, TCF12, BAF155, SPI1, BCL11A, BHLHE40, AR, GATA6, ZBTB16, DPF2, GATA2, IRF4, FOSL2, RNF2, TEAD4, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): CYYR1,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000166265,
- Related loop:
chr21:25600000-25625000~~chr21:25825000-25850000,
chr21:25600000-25625000~~chr21:25850000-25875000,
chr21:25750000-25775000~~chr21:25850000-25875000,
chr21:25825000-25850000~~chr21:26450000-26475000,
chr21:25825000-25850000~~chr21:26700000-26725000,
chr21:25825000-25850000~~chr21:26725000-26750000,
chr21:25850000-25875000~~chr21:26175000-26200000,
chr21:25850000-25875000~~chr21:26325000-26350000,
chr21:25850000-25875000~~chr21:26450000-26475000,
chr21:25850000-25875000~~chr21:26675000-26700000,
chr21:25850000-25875000~~chr21:26700000-26725000,