- Basic information
- CohesinDB ID: CDBP00415358
- Locus: chr21-25959897-25962359
-
Data sourse: ENCSR000BLD, ENCSR000HPG, GSE105028, GSE152721, GSE62063, ENCSR000EHX, GSE83726, GSE116344, GSE97394
-
Cell type: H1-hESC, RH4, Ramos, H9-hESC, IMR-90, SK-N-SH, HAP1, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: NIPBL,SMC3,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 56%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: AR, GATA6, NEUROD1, SOX2, NME2, HNF1A, OTX2, FOXA1
- Target gene symbol (double-evidenced CRMs): CYYR1,APP,GABPA
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 96
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25750000-25775000~~chr21:25950000-25975000,
chr21:25775000-25800000~~chr21:25950000-25975000,
chr21:25924913-25927132~~chr21:25962734-25964839,
chr21:25950000-25975000~~chr21:26050000-26075000,
chr21:25950000-25975000~~chr21:26075000-26100000,
chr21:25950000-25975000~~chr21:26125000-26150000,
chr21:25950000-25975000~~chr21:26150000-26175000,
chr21:25950000-25975000~~chr21:26250000-26275000,
chr21:25950000-25975000~~chr21:26375000-26400000,
chr21:25950000-25975000~~chr21:26525000-26550000,
chr21:25950000-25975000~~chr21:26800000-26825000,